Der "Pelican" steht eine höllische Reise bevor: Die Fahrt führt Philip Hasard Killigrew und seine Mannschaft durch die weitgehend unbekannte Magellanstraße mit ihren heftigen Gezeitenströmungen, vorbei an scharfen Klippen, mit dem Ziel, das sagenumwobene Terra Australis zu entdecken. Jenen Kontinent, den zuvor noch kein Menschenauge je erblickte ...
Autorentext
Dr. Robert A. Meyers, the Editor in Chief (EiC) of the Encyclopedia of Cell and Molecular Biology and Molecular Medicine, originated the Encyclopedia and continues responsibility for the project. Dr. Meyers has a Ph.D. in organic chemistry from UCLA and was a postdoctoral and faculty member at the California Institute of Technology. He is president of Ramtechlimited and is author or editor in chief of an additional twelve books and 20 technical papers as well as ten patents.
Zusammenfassung
Der "e;Pelican"e; steht eine hollische Reise bevor: Die Fahrt fuhrt Philip Hasard Killigrew und seine Mannschaft durch die weitgehend unbekannte Magellanstrae mit ihren heftigen Gezeitenstromungen, vorbei an scharfen Klippen, mit dem Ziel, das sagenumwobene Terra Australis zu entdecken. Jenen Kontinent, den zuvor noch kein Menschenauge je erblickte ...
Inhalt
Preface ix
Volume 1
Part I Basic Biology 1
1 Epigenetic Regulation in Pluripotent Stem Cells 3
Lin Liu and Lingyi Chen
2 Induced Pluripotent Stem Cells 41
Kazutoshi Takahashi and Shinya Yamanaka
3 Naturally Occurring Adult Pluripotent Stem Cells 63
Henry E. Young and Asa C. Black Jr
4 Spermatogonial stem cell (SSCs) system 95
G. Ian Gallicano and Shenglin Chen
5 Stem Cell Dormancy: Maintaining a Reserved Population 119
John M. Perry, Xi C. He, Ryohichi Sugimura and Linheng Li
6 Stem Cells in the Adult Brain: Neurogenesis 133
Michael A. Bonaguidi, Guo-li Ming, and Hongjun Song
7 Embryonic Stem Cells 151
Mahendra Rao
Part II Laboratory Methods 175
8 Cardiomyocytes from Human Embryonic Stem Cells 177
Xiu Qin Xu, Manasi Nandihalli, Kar Tong Tan, and William Sun
9 Cloned Mice from Adult Stem Cells 209
Haruko Obokata and Teruhiko Wakayama
10 Cloned Mice from Embryonic Stem Cells 233
Chong Li and Teruhiko Wakayama
11 Haploid Embryonic Stem Cells 255
Ni Hong and Yunhan Hong
12 Muscle Stem Cells: Their Discovery, Properties, and In-Vitro Manipulation 273
Sean McFarland, Ioanna Pagani, and Irina Conboy
13 Nuclear Transfer for Cloning Animals 299
Andras Dinnyes, Xiuchun Cindy Tian, and Bj¨orn Oback
14 Induction of Pluripotent Stem Cells from Umbilical Cord Blood 345
Kejin Hu and Igor Slukvin
15 Development and Renewal of Ventricular Heart Muscle from Intrinsic Progenitor Cells 371
William C.W. Chen and Bruno P´eault
Volume 2
Part III Stem Cell Therapy 389
16 Gene Therapy of Genetic Diseases of Blood Cells 391
Gabriela Kuftinec, Jennifer Wherley and Donald B. Kohn
17 Mesenchymal Stem Cells Characteristics, Niches, and Applications for Cell Therapy 429
Joni H. Yl¨ostalo and Thomas J. Bartosh
18 Stem Cells and Parkinson’s Disease 471
Emma Lane, Maria Sundberg, and Jan Pruszak
19 Stem Cell-Based Approaches to Spinal Cord Injury 503
Alexa L. Reeves and Hans Keirstead
20 Therapeutics against Cancer Stem Cells: Targeting the Root of Cancer 521
Kristen M. Smith and Catriona H. M. Jamieson
21 Translating Stem Cells to the Clinic: From Modeling Disease to Cellular Products 573
Emmanuel Nivet, Ignacio Sancho-Martinez, and Juan Carlos Izpisua Belmonte
Part IV Stem Cells and Disease 601
22 Cancer Stem Cells 603
Mei Zhang and Jeffrey M. Rosen
23 Normal and Neoplastic Stem Cells 627
Axel Schulenburg and Brigitte Marian
24 Prostate Tissue Stem Cells and Prostate Cancer Progression 655
Collene R. Jeter and Dean G. Tang
25 The Stem Cell Niche and Its Role in Self-Renewal, Aging, and Malignancy 677
Peter Breslin S.J., Andrew Volk and Jiwang Zhang
26 Stem Cells and Colon Cancer 727
Simone Di Franco, Antonina Benfante, Flora Iovino, Sebastiano Bonventre, Francesco Dieli, Giorgio Stassi and Matilde Todaro
Index 751