Nearly 44 million people have Alzheimer's or related dementia worldwide, according to the Alzheimer's Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer's and other forms of dementia.First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer's disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer's disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer's diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer's disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer's disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients. - Reviews recent developments of cognitive and clinical studies - Covers factors underlying the transition from mild cognitive impairment to Alzheimer's disease - Discusses different neural biomarkers underlying the development and treatment of Alzheimer's disease - Provides a comparison of the effectiveness of various types of treatments

Dr. Ahmed A. Moustafa is an associate professor in Cognitive and Behavioral Neuroscience at the Marcs Institute for Brain, Behavior, and Development, and in the School of Social Sciences and Psychology, Western Sydney University. He is trained in computer science, psychology, neuroscience, and cognitive science. His early training took place at Cairo University in mathematics and computer science. Before joining Western Sydney University as a lab director, he spent 11 years in America studying psychology and neuroscience. He
researches computational and neuropsychological studies of addiction, schizophrenia, Parkinson's disease, PTSD, and depression. He has published more than 150 papers in high-ranking journals including Science, PNAS, Journal of Neuroscience, Brain, Neuroscience and Biobehavioral Reviews, and Neuron.

1. The types of memory dysfunction in Alzheimer's disease
2. The prevalence of Depression in Alzheimer's disease
3. Quality of life in Alzheimer's disease
4. Cognitive and memory dysfunction in advanced-stage Alzheimer's disease
5. Past and future thinking processes in Alzheimer's disease
6. Factors underlying the transition from mild cognitive impairment to Alzheimer's disease
7. Understanding the complexity and subtypes of Alzheimer's disease
8. Different neural abnormalities in Alzheimer's disease: dissociating the role of cortical and subcortical structures
9. Recent studies of behavioral and neural markers of different symptoms in Alzheimer's disease
10. Enhancing autobiographical memory in Alzheimer's disease
11. Cognitive training and mindlessness for the treatment of Alzheimer's disease
12. The treatment of sleep disorders in Alzheimer's disease
13. Pharmacological treatment for Alzheimer' disease: recent advancement
14. The role of exercise and nutrition in the treatment of Alzheimer's disease