Exploring the growth in knowledge of particle properties and the variety of technological advances in particle manufacture, this book gives readers the tools they need to understand particulate science and its use in the industry. The authors cover particulate material, its form and production, sampling from bodies of powder, particle size descriptors and statistics, behavior of particles, instrumental analysis, particle size measurement and synergy of adopted techniques, physical behavior of a powder, and in vitro and in vivo performance criteria. They draw the components of particulate science into a single concise description of their integration in the context of product development.
Autorentext
Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey
Zusammenfassung
The pharmaceutical applications of powder technology have long been recognized. Yet while many books focus on aspects of powder formation and behavior, there has been no text that explores the power of particulate science in the design, manufacture, and control of quality medicines. Until now. A Guide to Pharmaceutical Particulate Science discusses
Inhalt
Introduction and Overview. Particulate Systems: Manufacture and Characterization. Sampling and Measurement Biases. Particle Size Descriptions and Statistics. Behavior of Particles. Instrumental Analysis. Methods of Particle Size Measurement and Their Importance for Specific Applications (Instrument Synergy). Particle Size Behavior and Physical Behavior of a Powder. Clinical Effect of Pharmaceutical Particulate Systems. General Conclusions. References. Index.