Asymmetric Organocatalysis 1 from the Science of Synthesis series gives an authoritative, broad overview of the field, compiled by 3 6 experts, as well as a critical presentation of the best organocatalytic and related methodologies available today for practical as ymmetric synthesis. It provides alternative, greener syntheses with simple and easily used catalysts helping avoid the use of expens ive and/or toxic metals.The reference work comprehensively covers all the catalysts and reactions within the activation modes Lewis base catalysis and Lewis acid catalysis. Typical or general experimental procedures as well as mechanistic, technical and theoretica l aspects are included, allowing the reader to clearly see how simple, clean and efficient this chemistry is. // The content of this e-book was originally published in December 2011.

Asymmetric Organocatalysis comprehensively covers all the catalysts and reactions within the activation modes Lewis base catalysis and Lewis acid catalysis. Typical or general experimental procedures as well as mechanistic, technical and theoretical aspects are included, allowing the reader to clearly see how simple, clean and efficient this chemistry is.

• Authoritative, broad overview of the field, compiled by 36 experts
• Critical presentation of the best organocatalytic and related methodologies available today for practical asymmetric synthesis
• Provides alternative, greener syntheses with simple and easily used catalysts helping avoid the use of expensive and/or toxic metals

1.1 Lewis Bases
1.1.1 Enamine Catalysis of Intramolecular Aldol Reactions
1.1.2 Enamine Catalysis of Intermolecular Aldol Reactions
1.1.3 Enamine Catalysis of Mannich Reactions
1.1.4 Enamine Catalysis of Michael Reactions
1.1.5 Enamine Catalysis of α-Functionalizations and Alkylations
1.1.6 SOMO and Radical Chemistry in Organocatalysis
1.1.7 Iminium Catalysis
1.1.8 Iminium Catalysis with Primary Amines
1.1.9 Applications of Aminocatalysis in Target-Oriented Synthesis
1.1.10 Tertiary Amine and Phosphine-Catalyzed Reactions of Ketenes and α-Halo Ketones
1.1.11 Chiral DMAP-Type Catalysts for Acyl-Transfer Reactions
1.1.12 Non-DMAP-Type Catalysts for Acyl-Transfer Reactions
1.1.13 Carbene-Catalyzed Benzoin Reactions
1.1.14 Carbene-Catalyzed Stetter Reactions
1.1.15 N-Heterocyclic Carbene Catalyzed Reactions of α-Functionalized Aldehydes
1.1.16 (Aza)-Morita–Baylis–Hillman Reactions
1.1.17 Phosphine Catalysis
1.2 Lewis Acids
1.2.1 Asymmetric Ketone and Iminium Salt Catalyzed Epoxidations
1.2.2 Lewis Acid Organocatalysts Other than Ketone and Iminium Salt Catalysts