When Garrett Walkinshaw pays a visit to his sister, he finds her murdered- throat sliced and nipples missing, his albino niece left emotionally scarred on her bed. Determined on getting revenge, the two set out after the killer, following a bloody trail of skin-lacking bodies. After Garrett's best friend- a recently freed slave- joins the road-trip hunt, they're forced to teach Garret' s niece the dark world of survival and assassination in the gritty, wild west, where they're met with myriad of roadblocks in the form of evil lawmen, bizarro brothers, a swamp witch, and more. Hap & Leonard meets Leon: The Professional, chasing down Ed Gein.