Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in May 2002.

Turning Information into Knowledge

Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series, Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise of 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. Science of Synthesis is designed to be the first point of reference when searching for a synthesis strategy.

This volume covers the synthesis of five-membered heterocyclic compounds with either two nitrogen or phosphorus atoms or five-membered heterocycles containing both one nitrogen and one phosphorus atom. The oxidation state of the described heterocycles corresponds to the maximum unsaturation. Maximum unsaturation means that the cyclic conjugation in the five-membered ring must not be interrupted by either an sp3-hybridized carbon atom or a heteroatom incapable of pi-conjugation.

For full information on the Science of Synthesis series, visit the Science of Synthesis Homepage.

Series Editors: D. Bellus, S. V. Ley, R. Noyori, M. Regitz, E. Schaumann, I. Shinkai, E. J. Thomas, B. M. Trost, P. J. Reider

Product Class 1: Pyrazoles
Product Class 2: 1H- and 2H-Indazoles
Product Class 3: Imidazoles
Product Class 4: Benzimidazoles
Product Class 5: Azaindolizines with Two Nitrogen Atoms in the Five-Membered Ring
Product Class 6: Azaphospholes and Azarsoles
Product Class 7: Diphospholes