In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem, the book then focuses on the latest findings of molecular mechanisms of drug resistance. Coverage provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment. It allows those who are interested in breast cancer therapy to get a jump-start on critical issues in breast cancer therapeutic resistance.
Inhalt
Overview of Resistance to Systemic Therapy in Patients with Breast Cancer.- Roles of Multidrug Resistance Genes in Breast Cancer Chemoresistance.- Therapy-Induced Apoptosis in Primary Tumors.- Cell Cycle Deregulation in Breast Cancer: Insurmountable Chemoresistance or Achilles' Heel?.- p53, BRCA1 and Breast Cancer Chemoresistance.- Integrin-Mediated Adhesion: Tipping the Balance between Chemosensitivity and Chemoresistance.- Insulin-Like Growth Factors and Breast Cancer Therapy.- EGF Receptor in Breast Cancer Chemoresistance.- Molecular Mechanisms of ErbB2-Mediated Breast Cancer Chemoresistance.- Estrogen Receptors in Resistance to Hormone Therapy.- Novel Approaches for Chemosensitization of Breast Cancer Cells: The E1A Story.
Titel
Breast Cancer Chemosensitivity
Autor
Editor
EAN
9780387740393
ISBN
978-0-387-74039-3
Format
E-Book (pdf)
Hersteller
Herausgeber
Veröffentlichung
30.12.2009
Digitaler Kopierschutz
Wasserzeichen
Dateigrösse
1.58 MB
Anzahl Seiten
175
Jahr
2009
Untertitel
Englisch
Unerwartete Verzögerung
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