This comprehensive review of the histopathology of the human nail will act as a masterclass for all dermatologists, dermatopathologists, and nail-interested pathologists who have to interpret histological sections of nail tissue, which can be challenging for many reasons.

Eckart Haneke, MD

Department of Dermatology, Inselspital, University of Bern, Switzerland

Dermatology Practice Dermaticum, Freiburg, Germany

Centro de Dermatología Epidermis, Instituto CUF, Porto, Portugal

Kliniek voor Huidziekten, Universitair Ziekenhuis, Ghent, Belgium

Development, structure, and function of the nail. Technical aspects: biopsy, processing, sectioning, staining, and reading the slides; nail glossary. Inflammatory dermatoses affecting the nail. Infections and infestations affecting the nail. Nail changes in systemic diseases and drug reactions. Genodermatoses affecting the nail. Nail-specific conditions. Epithelial and fibroepithelial tumors. Fibrous tumors. Vascular tumors. Tumors with adipocyte, myxoid, muscular, osseous and cartilaginous features. Neurogenic tumors. Histiocytic lesions. Hematogenous tumors. Melanocytic lesions. Metastases of the digital tip.