Differential diagnosis is at its most accurate and efficient when clinical presentation and histopathological features are considered in correlation with one another. With this being so, the expert team behind this atlas has integrated both perspectives to create an innovative and essential resource for all those involved with the diagnosis of tumors, cysts, and nevi. Almost 1,400 full-color images clearly illustrate common patterns and variants of tumorous lesions of the skin and are helpfully contextualized by concise, straightforward descriptions of key features and diagnostic clues.

Whether they are aspiring or experienced practitioners, dermatologists and pathologists of all levels will find this an insightful and practically applicable addition to their bookshelf. Its far-reaching and easy-to-navigate coverage of relevant diseases of the skin provides trainees with an excellent grounding in the area, while practicing specialists may benefit from its use as a tool for the differential diagnoses of borderline cases.

Atlas of Dermatopathology: Tumors, Nevi, and Cysts offers a uniquely balanced, clear, and comprehensive guide to what can be a difficult process, and will be of tremendous assistance tostudents, dermatologists, dermatopathologists, and pathologists everywhere.

Günter Burg, MD is Professor of Dermatology and Chairman Emeritus, University of Zurich, Switzerland.

Heinz Kutzner, MD is Professor of Dermatology, Institute of Dermatopathology, Friedrichshafen, Germany,

Werner Kempf, MD is Professor of Dermatology, Department of Dermatopathology, University of Zurich, Switzerland.

Josef Feit, MD is Associate Professor of Pathology, University of Ostrava, Czech Republic.

Bruce R. Smoller, MD is Professor and Chairman of the Department of Pathology and Laboratory Medicine, University of Rochester, NY, School of Medicine and Dentistry.

A fully illustrated diagnostic aid for dermatologists and pathologists at all levels

Differential diagnosis is at its most accurate and efficient when clinical presentation and histopathological features are considered in correlation with one another. With this being so, the expert team behind this atlas has integrated both perspectives to create an innovative and essential resource for all those involved with the diagnosis of tumors, cysts, and nevi. Almost 1,400 full-color images clearly illustrate common patterns and variants of tumorous lesions of the skin and are helpfully contextualized by concise, straightforward descriptions of key features and diagnostic clues.

Whether they are aspiring or experienced practitioners, dermatologists and pathologists of all levels will find this an insightful and practically applicable addition to their bookshelf. Its far-reaching and easy-to-navigate coverage of relevant diseases of the skin provides trainees with an excellent grounding in the area, while practicing specialists may benefit from its use as a tool for the differential diagnoses of borderline cases. As with the authors' previous work on inflammatory dermatoses, Atlas of Dermatopathology: Practical Differential Diagnosis by Clinicopathologic Pattern, this important text:

• Takes an effective, pattern-based approach to dermatologic diagnosis
• Matches clinical and histopathologic perspectives to give a fuller diagnostic picture
• Aids accurate diagnosis with almost 1,400 illustrative images
• Is written and designed to be easily consulted in everyday practice
• Presents contributions from internationally renowned dermatopathologists

Atlas of Dermatopathology: Tumors, Nevi, and Cysts offers a uniquely balanced, clear, and comprehensive guide to what can be a difficult process, and will be of tremendous assistance tostudents, dermatologists, dermatopathologists, and pathologists everywhere.

Preface xv

Acknowledgments xvii

1 EPIDERMIS 1

Nevi 2

Epidermal Nevus 2

Variant: Inflammatory Linear Verrucous Epidermal Nevus (ILVEN) 3

Keratoses 4

Seborrheic Keratosis (SK) and Variants 4

Variant: Acanthotic Seborrheic Keratosis 4

Variant: Reticulated, Pigmented Seborrheic Keratosis 6

Variant: Flat Seborrheic Keratosis 6

Variant: Papillomatous Seborrheic Keratosis 7

Variant: Activated (Irritated) Seborrheic Keratosis 7

Variant: Dermatosis Papulosa Nigra 7

Variant: Melanoacanthoma (Pigmented Seborrheic Keratosis) 8

Variant: Clonal (Intraepidermal) Seborrheic Keratosis (Borst Jadassohn) 9

Variant: Seborrheic Keratosis with Monster Cells (Bowenoid) 10

Variant: Hyperkeratotic Seborrheic Keratosis (Stucco Keratosis) 11

Confluent and Reticulate Papillomatosis (Gougerot and Carteaud) 12

Reticulate Pigmented Anomaly of the Flexures (DowlingDegos Disease) 13

Acanthosis Nigricans 14

Solar (Actinic) Keratosis 15

Variant: Acantholytic Solar Keratosis 16

Variant: Atrophic Solar Keratosis 16

Variant: Lichen PlanusLike Solar Keratosis 17

Variant: Hypertrophic (Bowenoid) Solar Keratosis 18

Cornu Cutaneum 18

Acanthomas, NonViral 19

Solar Lentigo 19

Callus, Factitial Acanthoma 20

Knuckle Pads (Chewing Pads) 21

Pale (Clear) Cell Acanthoma 22

Large Cell Acanthoma 23

Differential Diagnosis: Epidermolytic Acanthoma 24

Differential Diagnosis: Congenital Ichthyosiform Erythroderma 25

Acantholytic Acanthoma 26

Warty Dyskeratoma 27

Porokeratoma (Porokeratosis Mibelli) 30

Acanthomas, Viral 31

Verruca Vulgaris 31

Variant: Verruca Plana 33

Variant: Condyloma Acuminatum 34

Bowenoid Papulosis 35

Acrokeratosis Verruciformis (Hopf) 37

Molluscum Contagiosum 38

Pseudocarcinomas and Neoplasms with Intermediate Malignant Potential 40

Keratoacanthoma (KA) 40

Epithelioma Cuniculatum (Verrucous Carcinoma) (EC/VC) 44

Papillomatosis Cutis Carcinoides 45

Florid Papillomatosis of the Oral Cavity (Oral Verrucous Carcinoma) 46

BuschkeLöwenstein Tumor (Giant Condyloma) 47

Malignant Epidermal Neoplasms 48

Bowen's Disease (Carcinoma in situ) 48

Variant: Clear Cell Bowen's Disease 50

Variant: Cutaneous Horn (Cornu Cutaneum) on Bowen's Disease 51

Variant: Pigmented (Anogenital) and Clonal Bowen's Disease 52

Variant: Erythroplasia of Queyrat and Vulvar Intraepithelial Neoplasia 53

Basal Cell Carcinoma (BCC) 54

Variant: Nodular BCC 54

Variant: Infundibulocystic BCC 56

Variants of BCC With Ductal, Matrical or Sebaceous Differentiation 57

Variant: Superficial BCC 60

Variant: Pigmented BCC 61

Variant: AdenoidCystic BCC 62

Variant: Sclerodermiform (Morpheaform) BCC 64

Clinical Variants: Ulcerating BCCs 66

Histological Variants: Metatypic BCC with Squamoid Differentiation 67

Syndromatic BCC (Basal Cell Nevus Syndrome, GorlinGoltz) 69

Fibroepithelioma of Pinkus 70

Squamous Cell Carcinoma (SCC) 72

Variant: WellDifferentiated SCC 72

Variant: Acantholytic SCC (Epithelioma Spinocellulare Segregans of Delacretaz) 74

Variant: Myxoid SCC 76

Variant: Follicular (Infundibular) SCC 77

Variant: Spindle Cell (Fusicellular) SCC 78

Squamous Cell Carcinomas in Special Sites 79

2 ADNEXAL 85

Sweat Gland Differentiation 86

Nevi, Hyperplasias, and Benign Adnexal Neoplasms (BAN) 86

Eccrine Differentiation 86

Apocrine Differentiation 93

Malignant Adnexal Neoplasms 105

Eccrine Differentiation 105

Apocrine Differentiation 109…