This introductory text provides a student-friendly review of
essential immunity and immunopathology topics. Key concepts are
introduced in an incremental fashion to provide a thorough overview
of the field.
Closely tailored to the undergraduate immunology curriculum,
Part 1 outlines basic immunology, while Part 2 covers more
disease-related and clinical aspects. The new edition of this
popular title features a fully updated overview of the roles and
regulation of the cells and molecules of the immune system. Key
point summaries have been expanded, and key objectives added to the
start of each chapter, to help the reader focus on the essential
'take-home' messages. Readers can then test themselves
using the brand new self-assessment section containing
problem-solving questions and extended matching questions
(EMQs).
Including simple, memorable illustrations and quick reference
tables, Lecture Notes: Immunology provides the perfect
distillation of information for easy recall at revision time, and
is ideal for both the novice and those with some prior knowledge of
the field.
Autorentext
Ian Todd is at Queen's Medical Centre, Nottingham, UK
Gavin Spickett is at Royal Victoria Infirmary, Newcastle Upon Tyne, UK
Zusammenfassung
This introductory text provides a student-friendly review of essential immunity and immunopathology topics. Key concepts are introduced in an incremental fashion to provide a thorough overview of the field.
Closely tailored to the undergraduate immunology curriculum, Part 1 outlines basic immunology, while Part 2 covers more disease-related and clinical aspects. The new edition of this popular title features a fully updated overview of the roles and regulation of the cells and molecules of the immune system. Key point summaries have been expanded, and key objectives added to the start of each chapter, to help the reader focus on the essential 'take-home' messages. Readers can then test themselves using the brand new self-assessment section containing problem-solving questions and extended matching questions (EMQs).
Including simple, memorable illustrations and quick reference tables, Lecture Notes: Immunology provides the perfect distillation of information for easy recall at revision time, and is ideal for both the novice and those with some prior knowledge of the field.
Inhalt
Preface to the Sixth Edition, v
From the Preface to the First Edition, vi
Key to symbols used in the figures, vii
An overview of the immune system, viii
Part 1 Immunity and the Immune System
1 The nature of immunity, 3
2 Immune recognition, 14
3 Lymphocyte development and activation, 30
4 Lymphocyte interactions, cytokines and the lymphoid system, 40
5 Immunoglobulins, 55
6 Complement, 69
7 Phagocytes, 76
8 Mast cells, basophils and eosinophils, 82
9 Killer cells, 89
Part 2 Immunopathology
10 Immunity and infection, 97
11 Primary and secondary immunodeficiency disorders, 112
12 The generation of tissue-damaging responses, 134
13 Mechanisms of immunological tissue damage, 153
14 Lymphoproliferative disease, 165
15 Transplantation, 177
16 Immunological therapy, 188
Part 3 Self-assessment
Self-assessment questions, 199
Self-assessment answers, 209
Index, 215