This two-volume work focuses on the mathematical aspects of Darwinian evolution starting from the basic model of stochastic evolution of a single isolated locus in the presence of mutation to the multi-locus models of sexual and asexual populations. Volume 2 discusses the inference of fi tness landscape from DNA sequence data, discovery of the evolutionary roles of enygmatic traits, co-evolution of adversarial species, and various applications to virus evolution.

Igor M. Rouzine, Russian Academy of Sciences, Russian Federation.