- Covers all the essentials from tissue homeostasis and biocompatibility to cardiovascular engineering and regulations
- 22 chapters from internationally recognized authors, provide a comprehensive introduction for engineers and life scientists, including biomedical engineers, chemical and process engineers, materials scientists, biologists and medical students
- Full colour throughout, with clear development of understanding through frequent examples, experimental approaches and the latest research and developments.
Jan de Boer is a professor of Applied Cell Biology at the Laboratory of Cell Biology-Inspired Tissue Engineering, University of Maastricht, The Netherlands, where his team performs innovative research on molecular and cellular engineering of bone tissue. The research program is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology to streamline the wealth of biological knowledge to real clinical applications. He is chair of the Netherlands Society of Biomaterials and Tissue Engineering, and co-founder of the biotech company Materiomics B.V.
Autorentext
Clemens van Blitterswijk graduated as cell biologist from Leiden University in 1982, defending his PhD thesis in 1985 at the same university. Today his research focuses on tissue engineering and regenerative medicine, forming a unique basis of multidisciplinary research between materials and life sciences. Van Blitterswijk has authored and co-authored more than 380 peer reviewed papers (H index 90, Scopus); is one of the most frequently cited Dutch scientists in TE; the applicant and co-applicant of over 100 patents; has guided 50 PhD candidates through their thesis as supervisor or co-supervisor and currently has 30 PhD candidates under his supervision. Dr. van Blitterswijk received a number of prestigious international awards including the George Winter award of the European society for Biomaterials, the Career Achievement Award of the Tissue Engineering and Regenerative Medicine International Society and is a member of the KNAW (The Royal Netherlands Academy of Arts and Sciences).
Klappentext
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students and professionals who are developing their knowledge of this important topic. Key topics covered include stem cells; morphogenesis and cellular signaling; the extracellular matrix; biocompatibility; scaffold design and fabrication; controlled release strategies; bioreactors; tissue engineering of skin, cartilage, bone and organ systems; and ethical issues.
- Covers all the essentials from tissue homeostasis and biocompatibility to cardiovascular engineering and regulations
- 22 chapters from internationally recognized authors, provide a comprehensive introduction for engineers and life scientists, including biomedical engineers, chemical and process engineers, materials scientists, biologists and medical students
- Full colour throughout, with clear development of understanding through frequent examples, experimental approaches and the latest research and developments
Inhalt
Morphogenesis; Tissue Homeostasis; Regeneration; Stem cells; Extracellular matrix; Scaffolds: 1, physicochemical properties; 2, design at the macro, micro and nano level; 3, dissolution and degradation mechanisms; Biocompatibility; Cellular signaling; Controlled release systems; Cell source; Cell culture; Cell nutrition; Remodeling and integration into host tissue; Tissue engineering of 1, skin & corneal epithelium; 2, bone; 3, cartilage; Cardiovascular tissue engineering; Organ systems; Quality systems applicable to tissue engineering; EC & FDA regulations; Ethical aspects.