Exploring how to apply in vitro/in vivo correlations for controlled release dosage forms, Bioavailability of Drug Delivery Systems: Mathematical Modeling clearly elucidates this complex phenomena and provides a guide for the respective mathematical modeling. The book introduces mathematical modeling methods for calculating the profiles of plasma le
Autorentext
Jean-Maurice Vergnaud, Iosif-Daniel Rosca
Inhalt
Definitions. Intravenous Administration. Oral Dosage Forms With Immediate Release. Kinetics of Drug Release From Oral Sustained Dosage Forms. Bibliography on In Vitro/In Vivo Correlations. Plasma Drug Level With Diffusion-Controlled Dosage Forms. Plasma Drug Level With Erosion-Controlled Dosage Forms. Effect of Non-Compliance on the Plasma Drug Level. Drug Transfer in Various Tissues. Process of Transdermal Drug Transfer.