Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. A practical guide which explains how to carry out the numerical analysis of matter transfer - a vital process when examining the formulation of oral dosage forms with controlled drug release. The author models the process of drug delivery using numerical analysis and computerization.
Inhalt
Part 1 Mathematical treatment of diffusion: the plane dosage forms; cylinder of finite length; spherical dosage forms. Part 2 Numerical analysis for diffusion: plane dosage forms; cylinder of finite length; spherical dosage forms; other shapes; one or two matter transfers; models taking into account the swelling of the polymer matrix. Part 3 Description of various oral dosage forms: drug dispersed in a non-erodible polymer matrix, plane, spherical; drug dispersed in an erodible polymer matrix; dosage forms made of a core and shell, with an erodible shell; dosage forms made of a core and shell, with a non-erodible shell; dosage forms able to deliver the drug when the solubility of the drug is very low; problem of drying dosage forms made of drug and polymer.