This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.
Inhalt
1. Abnormal Claisen rearrangement.- 2. Alder ene reaction.- 3. Aldol condensation.- 4. Allan-Robinson reaction.- 5. Alper carbonylation.- 6. Amadori rearrangement.- 7. Angeli-Rimini hydroxamic acid synthesis.- 8. ANRORC mechanism.- 9. Arndt-Eistert homologation.- 10. Auwers reaction.- 11. Baeyer-Drewson indigo synthesis.- 12. Baeyer-Villiger oxidation.- 13. Baker-Venkataraman rearrangement.- 14. Bamberger rearrangement.- 15. Bamford-Stevens reaction.- 16. Bargellini reaction.- 17. Bartoli indole synthesis.- 18. Barton decarboxylation.- 19. Barton-McCombie deoxygenation.- 20. Barton nitrite photolysis.- 21. Baylis-Hillman reaction.- 22. Beckmann rearrangement.- 23. Beirut reaction.- 24. Benzilic acid rearrangement.- 25. Benzoin condensation.- 26. Bergman cyclization.- 27. Biginelli pyrimidone synthesis.- 28. Birch reduction.- 29. Bischler-Möhlau indole synthesis.- 30. Bischler-Napieralski reaction.- 31. Blaise reaction.- 32. Blanc chloromethylation reaction.- 33. Boekelheide reaction.- 34. Boger pyridine synthesis.- 35. Boord reaction.- 36. Borsche-Drechsel cyclization.- 37. Boulton-Katritzky rearrangement.- 38. Bouveault aldehyde synthesis.- 39. Bouveault-Blanc reduction.- 40. Boyland-Sims oxidation.- 41. Bradsher reaction.- 42. Brook rearrangement.- 43. Brown hydroboration reaction.- 44. Bucherer carbazole synthesis.- 45. Bucherer reaction.- 46. Bucherer-Bergs reaction.- 47. Buchner-Curtius-Schlotterbeck reaction.- 48. Buchner method of ring expansion.- 49. Buchwald-Hartwig C-N bond and C-O bond formation reactions.- 50. Burgess dehydrating reagent.- 51. Cadiot-Chodkiewicz coupling.- 52. Cannizzaro dispropotionation reaction.- 53. Carroll rearrangement.- 54. Castro-Stephens coupling.- 55. Chapman rearrangement.- 56. Chichibabin amination reaction.- 57. Chichibabin pyridine synthesis.- 58. Chugaev reaction.- 59. Ciamician-Dennsted rearrangement.- 60. Claisen condensation.- 61. Claisen rearrangement.- 62. Clarke-Eschweiler reductive alkylation of amines.- 63. Clemmensen reduction.- 64. Combes quinoline synthesis.- 65. Conrad-Limpach reaction.- 66. Cook-Heilbron thiazole synthesis.- 67. Cope elimination reaction.- 68. Cope, oxy-Cope, and anionic oxy-Cope rearrangements.- 69. Corey-Bakshi-Shibata (CBS) reduction.- 70. Corey-Chaykovsky reaction.- 71. Corey-Fuchs reaction.- 72. Corey-Kim oxidation.- 73. Corey-Winter olefin synthesis.- 74. Cornforth rearrangement.- 75. Criegee glycol cleavage.- 76. Criegee mechanism of ozonolysis.- 77. Curtius rearrangement.- 78. Dakin oxidation.- 79. Dakin-West reaction.- 80. Danheiser annulation.- 81. Darzens glycidic ester condensation.- 82. Davis chiral oxaziridine reagent.- 83. de Mayo reaction.- 84. Demjanov rearrangement.- 85. Dess-Martin periodinane oxidation.- 86. Dieckmann condensation.- 87. Diels-Alder reaction.- 88. Dienone-phenol rearrangement.- 89. Di-?-methane rearrangement.- 90. Doebner reaction.- 91. Doebner-von Miller reaction.- 92. Doering-LaFlamme allene synthesis.- 93. Dornow-Wiehler isoxazole synthesis.- 94. Dötz reaction.- 95. Dowd ring expansion.- 96. Dutt-Wormall reaction.- 97. Eglinton reaction.- 98. Eschenmoser coupling reaction.- 99. Eschenmoser-Tanabe fragmentation.- 100. Etard reaction.- 101. Evans aldol reaction.- 102. Favorskii rearrangement and Quasi-Favorskii rearrangement.- 103. Feist-Bénary furan synthesis.- 104. Ferrier rearrangement.- 105. Finkelstein reaction.- 106. Fischer-Hepp rearrangement.- 107. Fischer indole synthesis.- 108. Fischer-Speier esterification.- 109. Fleming oxidation.- 110. Forster reaction.- 111. Frater-Seebach alkylation.- 112. Friedel-Crafts reaction.- 113. Friedländer synthesis.- 114. Fries rearrangement.- 115. Fritsch-Buttenberg-Wiechell rearrangement.- 116. Fujimoto-Belleau reaction.- 117. Fukuyama amine synthesis.- 118. Gabriel synthesis.- 119. Gassman indole synthesis.- 120. Gattermann-Koch reaction.- 121. Gewald aminothiophene synthesis.- 122. Glaser coupling.- 123. Gomberg-Bachmann reaction.- 124. Gribble indole reduction.- 125. Gribble reduction of diaryl ketones.- 126. Grignard reaction.- 127. Grob fragmentation.- 128. Guareschi-Thorpe condensation.- 129. Hajos-Wiechert reaction.- 130. Haller-Bauer reaction.- 131. Hantzsch pyridine synthesis.- 132. Hantzsch pyrrole synthesis.- 133. Haworth reaction.- 134. Hayashi rearrangement.- 135. Heck reaction.- 136. Hegedus indole synthesis.- 137. Hell-Volhardt-Zelinsky reaction.- 138. Henry reaction (nitroaldol reaction).- 139. Herz reaction.- 140. Heteroaryl Heck reaction.- 141. Hiyama cross-coupling reaction.- 142. Hoch-Campbell aziridine synthesis.- 143. Hodges-Vedejs metallation of oxazoles.- 144. Hofmann rearrangement (Hofmann degradation reaction).- 145. Hofmann-Löffler-Freytag reaction.- 146. Hofmann-Martius reaction (Reilly-Hickinbottom rearrangement).- 147. Hooker oxidation.- 148. Horner-Wadsworth-Emmons reaction.- 149. Houben-Hoesch synthesis.- 150. Hunsdiecker reaction.- 151. Ing-Manske procedure.- 152. Jacobsen-Katsuki epoxidation.- 153. Jacobsen rearrangement.- 154. Japp-Klingemann hydrazone synthesis.- 155. Julia-Lythgoe olefination.- 156. Kahne glycosidation.- 157. Keck stereoselective allylation.- 158. Keck macrolactonization.- 159. Kemp elimination.- 160. Kennedy oxidative cyclization.- 161. Kharasch addition reaction.- 162. Knöevenagel condensation.- 163. Knorr pyrrole synthesis.- 164. Koch carbonylation reaction (Koch-Haaf carbonylation reaction).- 165. Koenig-Knorr glycosidation.- 166. Kolbe electrolytic coupling.- 167. Kolbe-Schmitt reaction.- 168. Kostanecki reaction.- 169. Krapcho decarboxylation.- 170. Kröhnke reaction (pyridine synthesis).- 171. Kumada cross-coupling reaction.- 172. Larock indole synthesis.- 173. Lawesson's reagent.- 174. Leuckart-Wallach reaction.- 175. Lieben haloform reaction.- 176. Liebeskind-Srogl coupling.- 177. Lossen rearrangement.- 178. Luche reduction.- 179. McFadyen-Stevens reduction.- 180. McLafferty rearrangement.- 181. McMurry coupling.- 182. Madelung indole synthesis.- 183. Mannich reaction.- 184. Marshall boronate fragmentation.- 185. Martin's sulfurane dehydrating reagent.- 186. Masamune-Roush conditions.- 187. Meerwein arylation.- 188. Meerwein-Ponndorf-Verley reduction.- 189. Meinwald rearrangement.- 190. Meisenheimer complex.- 191. Meisenheimer rearrangement.- 192. Meyer-Schuster rearrangement.- 193. Michael addition.- 194. Michaelis-Arbuzov phosphonate synthesis.- 195. Midland reduction.- 196. Miller-Loudon-Snyder nitrile synthesis.- 197. Mislow-Evans rearrangement.- 198. Mitsunobu reaction.- 199. Miyaura boration reaction.- 200. Moffatt oxidation.- 201. Morgan-Walls reaction (Pictet-Hubert reaction).- 202. Mori-Ban indole synthesis.- 203. Morin rearrangement.- 204. Mukaiyama aldol reaction.- 205. Mukaiyama esterification.- 206. Myers-Saito cyclization.- 207. Nametkin rearrangement (retropinacol rearrangement).- 208. Nazarov cyclization.- 209. Neber rearrangement.- 210. Nef reaction.- 211. Negishi cross-coupling reaction.- 212. Nenitzescu indole synthesis.- 213. Nicholas reaction.- 214. Noyori asymmetric hydrogenation.- 215. Nozaki-Hiyama-Kishi reaction.- 216. Oppenauer oxidation.- 217. Orton rearrangement.- 218. Overman rearrangement.- 219. Paal-Knorr furan synthesis.- 220. Paal-Knorr pyrrole synthesis.- 221. Parham cyclization.- 222. Passerini reaction.- 223. Paterno-Büchi reaction.- 224. Pauson-Khand cyclopentenone synthesis.- 225. Payne rearrangement…