This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmenta

1. Dose-response Relationships. 2. Factors Affecting Toxic Responses: Disposition. 3. Factors Affecting Toxic Responses: Metabolism. 4. Factors Affecting Metabolism, Disposition and Toxicity. 5. Toxic Responses to Foreign Compounds. 6. Biochemical Mechanisms of Toxicity: Specific Examples.