Evidence-based Clinical Practice (EBCP) is the conscientious, explicit, and judicious use of current best external evidence in making decisions about the care of individual patients. In neurology, practice has shifted from a rich, descriptive discipline to one of increasingly diagnostic and therapeutic interventions. Providing a comprehensive review of the current best evidence, Neurology: An Evidence-Based Approach presents this type of evidence in a concise, user-friendly and easily accessible manner. The three co-editors of this important volume are linked in their passion for evidence-based clinical practice in the clinical neurological sciences, connected to a common historical origin at the University of Western Ontario (UWO), London, Ontario Canada and influenced directly by Evidence-Based Medicine teachings of McMaster University, Hamilton, Ontario Cananda. The book is organized in three sections: Basics of Evidence-Based Clinical Practice, with an introduction to the topic, a chapter on the evolution of the hierarchy of evidence, and another chapter on guidelines for rating the quality of evidence and grading the strength of recommendation. The second section, Neurological Diseases, provides an illuminating overview of evidence-based care in ten of the most common areas in neurologic practice. The final, third section provides an outstanding roadmap for teaching evidence-based neurology with a chapter on the Evidence-Based Curriculum. A superb contribution to the literature, Neurology: An Evidence-Based Approach offers a well designed, well written, practical reference for all providers and researchers interested in the evidence-based practice of neurology.

Table of Contents

Foreword Vladimir Hachinski

Preface Jorge G. Burneo, Bart M. Demaerschalk, Mary E. Jenkins

Part One Basics of Evidence-Based Clinical Practice

Chapter 1 Evidence-Based Clinical Practice and the Neurosciences

Jorge G. Burneo, Bart M. Demaerschalk, Mary E. Jenkins

Yngve Falck-Ytter and Gordon H. Guyatt

Part Two Neurological Diseases

Chapter 4 Stroke

Maria I. Aguilar and Bart M. Demaerschalk

Chapter 5 Headache

Esma Dilli and David W. Dodick

Chapter 6 Epilepsy

Jorge G. Burneo and Robert C. Knowlton

Chapter 7 Movement Disorders

Mary E. Jenkins, Janis M. Miyasaki, Oksana Suchowersky

Chapter 8 Cognitive and BehaviouralNeurology

Elizabeth Finger and Kirk R. Daffner

Chapter 9 Neuromuscular Disorders

Brian A. Crum, Devon I. Rubin, Elliot L. Dimberg, Brent P. Goodman

Chapter 10 Neuropathic Pain

Brent P. Goodman

Chapter 11 Acute Therapies and Disease-Modifying Therapies for Multiple Sclerosis

Khurram Bashir and Dean M. Wingerchuk

Chapter 12 Infections of the Nervous System

Nicholas L. King and Jorge G. Burneo

Chapter 13 Neurocritical Care

Rajat Dhar and Michael N. Diringer

Part Three The Evidence-Based Neurology Curriculum

Chapter 14 The Evidence-Based Neurology Curriculum

Lawrence Korngut and Miguel Bussière.