A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you've come to expect from the leading reference in the field - keeping you up to date with today's latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology.
- Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs.
- Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders.
- Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women's Hospital, all of whom bring a wealth of insight to this classic text.
- Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more.
- Uses an improved organization to enhance navigation.
Autorentext
Dr. Volpe received his M.D. degree from the Harvard Medical School, completed a Pediatric residency at the Massachusetts General Hospital, carried out a postdoctoral research fellowship at the NIH and trained in Pediatric Neurology at the Massachusetts General Hospital. He then served for 20 years on the faculty at Washington University in St. Louis, the last ten years the Stein Professor of Neurology and Director of the Division of Pediatric Neurology. In 1990 he was named Neurologist-in-Chief at the Boston Children's Hospital, Bronson Crothers Professor of Neurology at the Harvard Medical School, and Chairman of the Department of Neurology at Children's Hospital/Harvard Medical School. Under Dr. Volpe's leadership over the next 15 years, the Department of Neurology grew to a faculty size of over 50 child neurologists and neuroscientists. The clinical and research programs became the largest and most diverse of any child neurology facility in the world.
Dr. Volpe generally is credited with having pioneered the field of neonatal neurology. His work in that field has included both clinical and basic research. The principal focus of his research has been elucidation of the pathogenesis of the major forms of brain injury in the newborn, and prevention of this injury. He has contributed more than 300 original articles and his single-authored book, Neurology of the Newborn, over five editions, is considered "the bible" in the field. Previous reviews have characterized the book as "an extraordinary work of scholarship , "so comprehensive, it is beyond criticism , "a treasure for those interested in the neurologic disorders of the newborn , "the standard reference for all involved in the care of the newborn infant .
Dr. Volpe is also widely recognized for his dedication to the training of academic child neurologists and neonatologists, and many of his approximately 100 past trainees are key figures in programs in neonatal neurology throughout the world. He also has trained approximately 50 research fellows in clinical and basic research, most of whom hold academic positions worldwide.
He has received many awards nationally and internationally, including the most prestigious awards of major academic societies of pediatrics child neurology, and neonatology worldwide. In 1997 he was elected to the Institute of Medicine (National Academy of Medicine) of the U.S. National Academy of Sciences. In 2007 the Boston Children's Hospital created the Joseph J. Volpe Chair in Neurology, currently held by Dr. Basil Darras, one of the editors of this book.
In this sixth edition, Dr. Volpe has led a distinguished group of editors and authors, all of whom are former trainees and colleagues. The book retains the dedication to excellence apparent in the previous five single-authored editions.
Inhalt
Unit I: Human Brain Development
Overview
1. Neural Tube Development and Defects
2. Prosencephalic Development and Defects
3. Congenital Hydrocephalus
4. Cerebellar Development and Defects
5. Neuronal Proliferative Events and Defects
6. Neuronal Migrational Events and Defects
7. Organizational Events and Defects
8. Myelination Events and Defects
Unit II: Neurological Evaluation
Overview
9. Neurological Examination: Normal and Abnormal Features
10. Specialized Neurological Studies
11. Neurodevelopmental Followup
Unit III: Neonatal Seizures
Overview
12. Neonatal Seizures
Unit IV: Hypoxic-ischemic and Related Disorders
Overview
13. Pathophysiology General Principles
14. Encephalopathy of the Preterm - Neuropathology
15. Encephalopathy of the Preterm - Pathophysiology
16. Encephalopathy of the Preterm - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy
17. Intrauterine, Intrapartum Assessments in the Term Infant
18. Hypoxic Ischemic Injury in the Term Infant - Neuropathology
19. Hypoxic Ischemic Injury in the Term Infant - Pathophysiology
20. Hypoxic Ischemic Injury in the Term Infant - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy
21. Stroke in the Newborn
Unit V: Intracranial Hemorrhage
Overview
22. Intracranial/Hemorrhage - Supratentorial (Subdural, Subarachnoid, Intraventricular (Term Infant), Miscellaneous
23. Intracranial Hemorrhage Infratentorial/Cerebellar
24. Preterm IVH/Posthemorrhagic Hydrocephalus
Unit VI: Metabolic Encephalopathies
Overview
25. Glucose
26. Bilirubin
27. Amino acids
28. Organic acids
Unit VII: Degenerative Disorders
29. Degenerative Disorders of the Newborn
Unit VIII: Neuromuscular Disorders
Overview
30. Evaluation, Specialized Studies
31. Arthrogryposis Multiplex Congenita
32. Levels Above Lower Motor Neuron to Neuromuscular Junction
33. Muscle Involvement and Restricted Disorders
Unit IX: Intracranial Infections
Overview
34. Viral, Protozoan and Related Intracranial Infections
35. Bacterial and Fungal Intracranial Infections
Unit X: Perinatal Trauma
36. Injuries of Extracranial, Cranial, Intracranial, Spinal Cord and Peripheral Nervous System Structures
Unit XI: Intracranial Mass Lesions
37. Brain Tumors and Vein of Galen Malformations
Unit XII: Drugs and the Developing Nervous System
Overview
38. Passive Addiction and Teratogenic Effects