Sine syndromes (SSs) represent atypical forms of inflammatory rheumatic diseases, the courses of which are often severe. While the diagnosis of rheumatic diseases can be determined according to an established set ofdiagnostic criteria based on clinical characteristics and laboratory parameters, Sine Syndromes do not fulfill thestandard criteria used to assist in theclassification of patients with rheumatologicaldisorders. This concise book gives an overview of atypical courses in common inflammatory rheumatic diseases such as Wegener's granulomatosis, systemic sclerosis, Sjgren's syndrome, or systemic lupus erythematosus. Each chapter reviews similar cases reported in the literature and presents current data on treatment options. Drawing on their vast clinical experience, the editors provide a series of detailed case reports in order to illustrate the different types ofdisease. The book is intended to facilitate early diagnosis and effective therapy in patients where a schematic approach may not prove sufficient. Sine Syndromes in Rheumatology willserve as auseful and easily accessiblereference for specialists in rheumatology as well as for practitioners in the fields of internal medicine, pediatrics, and orthopedics.