Veresterungsreaktionen stellen ohne Zweifel eine der wichtigsten Reaktionen in der organischen Chemie dar. Obwohl es sich um eine "klassische" Reaktion mit einer langen Geschichte handelt, werden auch heute kontinuierlich neue Entwicklungen vorgestellt, die diese Umsetzung immer effektiver und vielseitiger machen. Veresterungen mit Lewis Säuren oder Basen, Metallalkoxiden oder Aminen, Enzymen oder Anhydriden, alle diese Varianten stellen die Vielschichtigkeit dieser Reaktion unter Beweis.
Dieses Buch von dem erfahrenen Autor Professor J. Otera faßt nun zum ersten Mal das Wissen dieser elementaren Reaktion mit allen Facetten umfassend zusammen. Angefangen von methodischen Grundlagen bis hin zu den praktischen Anwendungen bietet das Werk eine ausführliche Übersicht über diesen Reaktionstyp und erspart nicht nur bei praktischen Fragen dem Leser zeitraubende Literaturrecherchen. Deshalb sollte dieses Buch zur Standardliteratur eines jeden Organikers gehören.
Autorentext
Junzo Otera was born in Hyogo, Japan in 1943. He received undergraduate as well as graduate education in Osaka University. Immediately after earning the PhD degree in 1971, he became a research chemist in Central Research Laboratories of Kuraray Co.
In 1979, he moved to?Okayama University of Science as Associate Professor and has been Full Professor since 1986. In the meantime, he served as a visiting professor in many universities in Japan, USA, France, Spain, and Australia.
His research interests are focused on Lewis acid catalysts, heteroatom chemistry, and green process chemistry.
Zusammenfassung
Here, Professor J. Otera brings together for the first time the combined knowledge about this elementary yet multifaceted reaction. Starting from the methodical basics right up to practical applications, this book represents a comprehensive overview of this type of reaction, saving readers time-consuming research among the literature - and not just in practical matters. All set to become a standard reference for every organic chemist.
From the contents:
METHODOLOGY
Reaction of Alcohols with Carboxylic Acids and Their Derivatives
Reactions with Carboxylic Acids
Reaction with Esters: Transesterification
Reaction with Acid Anhydrides
Reaction with Acid Halides and Related Compounds
Conversion of Alcohols to Esters through Carbonylation
SYNTHETIC APPLICATIONS
Kinetic Resolution
Enzymatic Resolution
Nonenzymatic Resolution
Asymmetric Desymmetrization
Deacetylation through Transesterification
Selective Esterification
Applications to Natural Product Synthesis
New Reaction Media
Industrial Uses
Inhalt
Preface
Introduction
METHODOLOGY
Reaction of Alcohols with Carboxylic Acids and Their Derivatives
Reactions with Carboxylic Acids
Reaction with Esters: Transesterification
Reaction with Acid Anhydrides
Reaction with Acid Halides and Related Compounds
Conversion of Alcohols to Esters through Carbonylation
Conversion of Carboxylic Acids to Esters without Use of Alcohols
Reaction with Diazomethane
Reaction with Alkyl Halides
Reaction with Orthoesters
Ester-Interchange Reaction
SYNTHETIC APPLICATIONS
Kinetic Resolution
Enzymatic Resolution
Nonenzymatic Resolution
Asymmetric Desymmetrization
Miscellaneous Topics
Protection by Acylation
Deacetylation through Transesterification
Selective Esterification
Use of Stoichiometric Amounts of Reactants
Applications to Natural Product Synthesis
New Reaction Media
Industrial Uses