Protobiology as a physics of becoming emphasizes the dynamics underlying conservation laws, whereas the physics of being emphasize the dynamics presupposing conservation laws. Protobiology thus concerns itself with a convoluted problem of how both the law of motion and its boundary conditions develop with time without forgetting that these two are inseparable, in contrasts to the physics of being that assumes separability.

K. Matsuno

1. What is Protobiology 2. Internal Measurements 3. Equilibration 4. Intrinsic Irreversibility 5. Symmetry Breaking 6. Information 7. Protoreproduction 8. Equilibration in Development 9. Equilibration in Evolution 10. Equilibration in Ecology 11. Epilogue