Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts.* Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions.* New, detailed information on the pathogenesis and immunology of the Flavivirus family.* Descibes the technologies that have contributed to our current knowledge about the Flaviviruses.* Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease.* An exhaustive compendium of current and past knowledge on the Flavivirus family

Pathogenesis and Immunity
Molecular Determinants of Virulence: The Structural and Functional Basis for Flavivirus Attenuation
Genetic resistance to flaviviruses
Immunobiology of mosquito-borne encephalitic Flaviviruses
Immune Modulation by Flaviviruses
Mechanisms of virus-induced cell death
Dynamics of Flavivirus Infection in Mosquitos
Dynamics of Infection in Tick vectors and at the tick-host interface
Encephalitic viruses
Pathogenesis and Pathophysiology of Yellow Fever virus
Immunopathogenesis of dengue hemorrhagic fever
Immunology and Immunopathogenesis of Dengue Disease
Neutralization and Antibody-Dependent Enhancement of Dengue Viruses