The origin of life has been investigated by many researchers from various research fields, such as Geology, Geochemistry, Physics, Chemistry, Molecular Biology, Astronomy and so on. Nevertheless, the origin of life remains unsolved. One of the reasons for this could be attributed to the different approaches that researchers have used to understand the events that happened on the primitive Earth. The origins of the main three members of the fundamental life system, as gene, genetic code and protein, could be only separately understood with these approaches. Therefore, it is necessary to understand the origins of gene, the genetic code, tRNA, metabolism, cell structure and protein not separately but comprehensively under a common concept in order to understand the origin of life, because the six members are intimately related to each other.

In this monograph, the author offers a comprehensive hypothesis to explain the origin of life under a common concept. At the same time, the author offers the [GADV] hypothesis contrasting it with other current hypotheses and discusses the results of analyses of genes/proteins and the experimental data available in the exploration of the current knowledge in the field. This book is of interest for science students, researchers and the general public interested in the origin of life.



Autorentext
Kenji Ikehara received his degree in Industrial Chemistry from Kyoto University in 1968 and obtained his Ph.D. in 1976 at the section of Engineering of Kyoto University. He moved as research associate to Faculty of Science, the University of Tokyo, to associate professor, Nara Women's University and got promoted to full professor, Nara Women's University. He served as Director of the Faculty of Science, Nara Womens's University and as Director of the Nara Study Center of the Open University of Japan. He is also a fellow of the International Institute for Advanced Studies (IIAS) in Japan and Emeritus Professor of Nara Women's University. He served as Local Chair of International Conference, Origin 2014, which was held at Nara in 2014. He has published about 60 publications in international journals and contributed 3 chapters of international books as author, 1 book as author and 1 book as editor. He has participated in more than 100 congresses, presenting main, oral and poster communications in international and national congresses. His main research fields of interest are represented by the studies on origins of protein, genetic code, genes and life.

Klappentext

The origin of life has been investigated by many researchers from various research fields, such as Geology, Geochemistry, Physics, Chemistry, Molecular Biology, Astronomy and so on. Nevertheless, the origin of life remains unsolved. One of the reasons for this could be attributed to the different approaches that researchers have used to understand the events that happened on the primitive Earth. The origins of the main three members of the fundamental life system, as gene, genetic code and protein, could be only separately understood with these approaches. Therefore, it is necessary to understand the origins of gene, the genetic code, tRNA, metabolism, cell structure and protein not separately but comprehensively under a common concept in order to understand the origin of life, because the six members are intimately related to each other. 

In this monograph, the author offers a comprehensive hypothesis to explain the origin of life under a common concept. At the same time, the author offers the [GADV] hypothesis contrasting it with other current hypotheses and discusses the results of analyses of genes/proteins and the experimental data available in the exploration of the current knowledge in the field. This book is of interest for science students, researchers and the general public interested in the origin of life.



Inhalt
Introduction
1. Why has not the origin of life been solved still now?
1.1. The reasons from viewpoint of research methodology
1.2. How could the three main members in the fundamental life system be created through random processes?
1.3. Then, is it impossible to unravel the riddle of the origin of life?
2. My idea about the origin of life
2.1. I might be able to solve the riddle of the origin of life from my own viewpoint
2.2. The reason why I could reach a novel idea, with which the riddle of the origin of life might be solved
3. Overview of this book
References
Chapter 1: Modern Fundamental Life System
Abstract
1. Towards solving the riddle of the origin of life
1.1. The mechanism how life is living
1.2. Necessary matters for solving the riddle of the origin of life
1.3. Significance of theoretical approach
2. Overview of [GADV]-protein world hypothesis (GADV hypothesis)
2.1. Establishment process of the fundamental life system (Outline)
2.2. The steps from chemical evolution to the emergence of life
References
Chapter 2: The Origin of Protein
Abstract
Introduction
1. Towards solving the riddle of the origin of protein
1.1. Necessary matters for exploring the origin of protein
1.2. General structural features of modern protein (enzyme)
1.3. General functional features of modern protein (enzyme)
2. Structure formation of protein under the modern genetic system
3. The ideas on the origin of protein advocated by other researchers
3.A. The origin of protein-I: How was the first mature protein created?
3.B. The origin of protein-II: How have entirely new mature proteins been created?
3. 1. Amino acid sequence hypothesis
3.2. Protein structure hypothesis
3.3. Short peptide (motif) theory
3.4. The reason why the origin of protein-II has not been solved still now
4. My idea about the origin of protein
4.A. The origin of protein-I: How was the first mature protein created?
4.1. Chemical evolution
4.2. [GADV]-amino acids could be produced at large amounts through prebiotic means
4.3. Immature [GADV]-protein could be produced through a random process
4.4. [GADV]-amino acid composition is one of protein 0th -order structures
4.5. From production of immature protein to formation of double-stranded (GNC)ngene
4.6. The formation of the first ds-(GNC)nRNA led to creation of the first mature [GADV]-protein
4.7. Immature protein is pluripotent
4.B. The origin of protein-II: How has an entirely new mature protein been created?
4.8. Creation of an entirely new mature protein through the first double-stranded (GNC)nRNA
5. Discussion
6. Conclusion
References
Chapter 3: The Origin of Cell Structure
Abstract:
Introduction
1. Towards solving the riddle of the origin of cell structure
1.1. Necessary matters for exploration of the origin of cell structure
1.2. General structural features of modern cell (cell structure)
1.3. General functional features of modern cell (cell structure)
2. The ideas on the origin of cell structure advocated by other researchers
2.1. Amphiphile membrane theory
2.2. Protenoid microsphere theory
3. My idea on the origin of modern cell
3.1. For what purpose was the first cell structure created?
3.2. [GADV]-microsphere hypothesis
Titel
Towards Revealing the Origin of Life
Untertitel
Presenting the GADV Hypothesis
EAN
9783030710873
Format
E-Book (pdf)
Veröffentlichung
07.06.2021
Digitaler Kopierschutz
Wasserzeichen
Dateigrösse
7.52 MB
Anzahl Seiten
240