This new textbook on bacterial physiology is aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students' interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.

For several decades, bacteria have served as model systems to describe the life p- cesses of growth and metabolism. In addition, it is well recognized that prokaryotes have contributed greatly to the many advances in the areas of ecology, evolution, and biotechnology. This understanding of microorganisms is based on studies of members from both theBacteria andArchaea domains. With each issue of the various scienti?c publications, new characteristics of prokaryotic cells are being reported and it is - portant to place these insights in the context of the appropriate physiological processes. Structural and Functional Relationships in Prokaryotes describes the fundamental physiological processes for members of the Archaea and Bacteria domains. The - ganization of the book re?ects the emphasis that I have used in my 30 years of teaching a course of bacterial physiology. The philosophy used in the preparation of this book is to focus on the fundamental features of prokaryotic physiology and to use these features as the basis for comparative physiology. Even though diverse phenotypes have evolved from myriad genetic possibilities, these prokaryotes display considerable functional similarity and support the premise that there is a unity of physiology in the prokaryotes. The variations observed in the chemical structures and biochemical p- cesses are important in contributing to the persistence of microbial strains in a speci?c environment.

An Introduction to the Prokaryotic Cell.- The Cellular System.- Cellular Structures and Their Function.- The Plasma Membrane.- Cell Wall Structure.- The Cell Wall Matrix.- Capsules, Pili, and Internal Structures.- Profiles of Bacterial Growth.- Cell Motion, Sensing, and Communication.- Cellular Growth and Reproduction.- Physiological Basis for Growth in Extreme Environments.- Bioenergetics.- Electron Transport and Coupled Phosphorylation.- Transmembrane Movement: Mechanisms and Examples.- Metabolic Processes.- Pathways of Carbon Flow.- Organization and Cellular Processing.- Metabolism of Nitrogen and Sulfur.- Biometals.