Ocular Disease-a newly introduced companion volume to the classic Adler's Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world's leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color-with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. This comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment. - Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases. - Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease. - Features 330 full-color line artworks that translate difficult concepts and discussions into concise schematics for improved understanding and comprehension. - Provides the expert advice of internationally recognized editors with over 40 years of experience together with a group of world class contributors in basic science and clinical ophthalmology.
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SECTION 1 Cornea
1. Loss of corneal transparency
Russell L McCally
2. Abnormalities of corneal wound healing
Audrey M Bernstein
3. Wound healing after laser in situ keratomileusis and photorefractive keratectomy
Fabricio Witzel de Medeiros and Steven E Wilson
4. Genetics and mechanisms of hereditary corneal dystrophies
John D Gottsch
5. Fuchs' endothelial corneal dystrophy
Vinay Gutti, David S Bardenstein, Sudha Iyengar, and Jonathan H Lass
6. Keratoconus
M Cristina Kenney and Ronald N Gaster
7. Infectious keratitis
Michael S Gilmore, Susan R Heimer, and Ai Yamada
8. Corneal graft rejection
Daniel R Saban, Mohammad H Dastjerdi, and Reza Dana
9. Corneal edema
Daniel G Dawson and Henry F Edelhauser
10. Corneal angiogenesis and lymphangiogenesis
Chih-Wei Wu, David Ellenberg, and Jin-Hong Chang
11. Ocular surface restoration
Julie T Daniels, Genevieve A Secker, and Alex J Shortt
12. Herpetic keratitis
Pranita P Sarangi and Barry T Rouse
13. Ocular allergy
Neal P Barney, Ellen B Cook, James L Stahl, and Frank M Graziano
SECTION 2 Dry eye
14. The lacrimal gland and dry-eye disease
Darlene A Dartt
15. Immune mechanisms of dry-eye disease
Austin K Mircheff and Joel E Schechter
16. Disruption of tear lm and blink dynamics
Jianhua Wang and Anuj Chauhan
17. Abnormalities of eyelid and tear lm lipid
Gary N Foulks and Douglas Borchman
18 Dry eye: abnormalities of tear lm mucins
Ann-Christin Albertsmeyer and Ilene K Gipson
SECTION 3 Glaucoma
19. Steroid-induced glaucoma
Abbot F Clark, Xinyu Zhang, and Thomas Yorio
20. Biomechanical changes of the optic disc
Ian A Sigal, Michael D Roberts, Michael JA Girard, Claude F Burgoyne, and J Crawford Downs
21. Pigmentary dispersion syndrome and glaucoma
Michael G Anderson
22. Abnormal trabecular meshwork out ow
Paul A Knepper and Beatrice YJT Yue
23. Pressure-induced optic nerve damage
James C Tsai
24. Exfoliation (pseudoexfoliation) syndrome
Robert Ritch and Ursula Schlötzer-Schrehardt
25. Angle closure glaucoma
Shamira Perera, Nishani Amerasinghe, and Tin Aung
26. Central nervous system changes in glaucoma
Yeni N Yücel and Neeru Gupta
27. Retinal ganglion cell death in glaucoma
Heather R Pelzel and Robert W Nickells
28. Wound-healing responses to glaucoma surgery
Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, and Peng Tee Khaw
29. Blood owchanges in glaucoma
Leopold Schmetterer and Mark Lesk
SECTION 4 Lens
30. Biochemical mechanisms of age-related cataract
David C Beebe, Ying-Bo Shui, and Nancy M Holekamp
31. Posterior capsule opaci cation
Judith West-Mays and Heather Sheardown
32. Diabetes-associated cataracts
Peter F Kador
33. Steroid-induced cataract
Abbas Samadi
34. Presbyopia
Jane F Koretz
35. Restoration of accommodation
Stephen D McLeod and Michelle Trager Cabrera
36. Intraoperative oppy iris syndrome
Amy Lin and Roger F Steinert
SECTION 5 Neuro-ophthalmology
37. Optic neuritis
John R Guy and Xiaoping Qi
38. Abnormal ocular motor control
James A Sharpe and Arun Sundaram
39. Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri)
Deborah M Grzybowski and Martin Lubow
40. Giant cell arteritis
Lynn K Gordon
41. Ischemic optic neuropathy
Helen Danesh-Meyer
42. Optic nerve axonal injury
Daniela Toffoli and Leonard A Levin
43. Leber's hereditary optic neuropathy
Alfredo Sadun and Alice Kim
44. Optic atrophy
Nathan T Tagg and Randy H Kardon
45. Nystagmus
Frank Proudlock and Irene Gottlob
46. Toxic optic nerve neuropathies
FT "Fritz" Fraunfelder and FW "Rick" Fraunfelder
SECTION 6 Oncology
47. Uveal melanoma
Zélia MS Corrêa and J William Harbour
48. Genetics of hereditary retinoblastoma
Alejandra G de Alba Campomanes and Joan M O'Brien
49. Molecular basis of low-penetrance retinoblastoma
Katie Matatall and J William Harbour
50. Vasculogenic mimicry
Robert Folberg and Andrew J Maniotis
51. Treatment of choroidal melanoma
Aimee V Chappelow and Andrew P Schachat
52. Sebaceous cell carcinoma
Alon Kahana, Jonathan T Pribila, Christine C Nelson, and Victor M Elner
53. Neuro bromatosis
Robert Listernick and David H Gutmann
SECTION 7 Other
54 Phthisis bulbi
Ingo Schmack, Hans E Völcker, and Hans E Grossniklaus
55. Myopia
Terri L Young
56. Pathogenesis of Graves' ophthalmopathy
A Reagan Schiefer and Rebecca S Bahn
SECTION 8 Pediatrics
57. Duane syndrome
Joseph L Demer
58. Amblyopia
Robert F Hess and Nigel Daw
59 Strabismus
Christopher S von Bartheld, Scott A Croes, and L Alan Johnson
60. Albinism
Gerald F Cox and Anne B Fulton
61. Aniridia
Elias I Traboulsi
SECTION 9 Retina
62. Color vision defects
Maureen Neitz and Jay Neitz
63. Acute retinal vascular occlusive disorders
Sohan Singh Hayreh
64. Retinal photic injury: laboratory and clinical ndings
Daniel Organisciak and Marco Zarbin
65. Vascular damage in diabetic retinopathy
Timothy S Kern and Suber Huang
66. Neovascularization in diabetic retinopathy
Corey B Westerfeld and Joan W Miller
67. Diabetic macular edema
Pascale Massin, Michel Paques, and Jean-Antoine Pournaras
68. Dry age-related macular degeneration and age-related macular degeneration pathogenesis
Marco Zarbin and Janet S Sunness
69. Neovascular age-related macular degenerationDavid E Lederer, …