Principles and Practices of Polymer Mass Spectrometry helps readers acquire the skills necessary for selecting the optimal methods, handling samples, analyzing the data, and interpreting the results of the mass spectrometry of polymers. This guide describes the principles of polymer MS and best practices in polymer characterization. It discusses different approaches, including MALDI, ESI, TOF MS, and FT-MS. It provides a guide to developing appropriate sample preparation protocols for different polymers. Complete with examples of applications and experiments, this is an excellent reference for scientists, researchers, graduate students, and others.
Autorentext
Liang Li, PhD, is a Professor of Chemistry and a Canada Research Chair in Analytical Chemistry at the University of Alberta. He is an Editor of Analytical Chimica Acta and a member of the Advisory Boards for the Journal of the American Society for Mass Spectrometry, Canadian Journal of Chemistry, and Current Analytical Chemistry.
Klappentext
Tested and proven practices from the experts for successful polymer characterization and analysis
Written by a team of leading mass spectrometry experts, this book enables readers to avoid the many pitfalls that often occur during the MALDI MS analysis of synthetic polymers by guiding them through each step of the procedure. It carefully explains the principles of polymer mass spectrometry and sets forth the best practices in using MALDI MS, emphasizing the specific skills and techniques required for polymer analysis and characterization. With the book's careful guidance, readers gain new skills in:
- Selecting the optimal method to characterize a particular sample
- Preparing and handling samples
- Analyzing data and interpreting the results
Following an overview of MS and MALDI Mass Spectrometry for Synthetic Polymer Analysis, each chapter is dedicated to a specific technique or method, including:
- Time-of-flight MS for polymer characterization
- Tandem MS and polymer ion dissociation
- New approaches to data reduction in MS
- MALDI MS applications for industrial polymers
The authors of each chapter describe the underlying principles of the technique or method, its attributes in polymer characterization, shortcomings, and efforts for further development and improvement. Examples of applications and experiments are provided alongside tips to help readers perform seamless analyses.
Because of the great diversity in polymer chemistry, there is no universal approach for MALDI MS analysis of polymers. With this book, readers can choose and apply the right analytical protocol to characterize and analyze any polymer sample.
Zusammenfassung
MALDI Mass Spectrometry for Synthetic Polymer Analysis helps readers acquire the skills necessary for selecting the optimal methods, handling samples, analyzing the data, and interpreting the results of the mass spectrometry of polymers. This guide describes the principles of polymer MS and best practices in polymer characterization. It discusses different approaches, including MALDI, ESI, TOF MS, and FT-MS. It provides a guide to developing appropriate sample preparation protocols for different polymers. Complete with examples of applications and experiments, this is an excellent reference for scientists, researchers, graduate students, and others.
Inhalt
PREFACE vii
CONTRIBUTORS ix
CHAPTER 1 OVERVIEW OF MS AND MALDI MS FOR POLYMER ANALYSIS 1
Liang Li
CHAPTER 2 IONIZATION PROCESSES AND DETECTION IN MALDI-MS OF POLYMERS 9
Renato Zenobi
CHAPTER 3 TIME-OF-FLIGHT MASS SPECTROMETRY FOR POLYMER CHARACTERIZATION 27
Liang Li and Randy M. Whittal
CHAPTER 4 POLYMER ANALYSIS WITH FOURIER TRANSFORM MASS SPECTROMETRY 53
Sabine Borgmann and Charles L. Wilkins
CHAPTER 5 TANDEM MASS SPECTROMETRY AND POLYMER ION DISSOCIATION 85
Michael J. Polce and Chrys Wesdemiotis
CHAPTER 6 CONVENTIONAL MALDI SAMPLE PREPARATION 129
Kevin G. Owens and Scott D. Hanton
CHAPTER 7 SOLVENT-FREE MALDI SAMPLE PREPARATION 159
Sarah Trimpin
CHAPTER 8 MALDI MASS SPECTROMETRY FOR THE QUANTITATIVE DETERMINATION OF POLYMER MOLECULAR MASS DISTRIBUTION 187
Charles M. Guttman and William E. Wallace
CHAPTER 9 NEW APPROACHES TO DATA REDUCTION IN MASS SPECTROMETRY 205
William E. Wallace, Anthony J. Kearsley, and Charles M. Guttman
CHAPTER 10 MALDI-MS/MS FOR POLYMER STRUCTURE AND COMPOSITION ANALYSIS 219
Anthony T. Jackson
CHAPTER 11 LC-MALDI MS FOR POLYMER CHARACTERIZATION 247
Steffen M. Weidner and Jana Falkenhagen
CHAPTER 12 MALDI MS APPLICATIONS FOR INDUSTRIAL POLYMERS 267
Scott D. Hanton and Kevin G. Owens
INDEX 289