Proven and tested guidelines for designing ideal labs for
scientific investigations

Now in its Fourth Edition, Guidelines for Laboratory
Design continues to enable readers to design labs that make it
possible to conduct scientific investigations in a safe and healthy
environment. The book brings together all the professionals who are
critical to a successful lab design, discussing the roles of
architects, engineers, health and safety professionals, and
laboratory researchers. It provides the design team with the
information needed to ask the right questions and then determine
the best design, while complying with current regulations and best
practices.

Guidelines for Laboratory Design features concise,
straightforward advice organized in an easy-to-use format that
facilitates the design of safe, efficient laboratories. Divided
into five sections, the book records some of the most important
discoveries and achievements in:

* Part IA, Common Elements of Laboratory Design, sets forth
technical specifications that apply to most laboratory buildings
and modules

* Part IB, Common Elements of Renovations, offers general design
principles for the renovation and modernization of existing
labs

* Part II, Design Guidelines for a Number of Commonly Used
Laboratories, explains specifications, best practices, and
guidelines for nineteen types of laboratories, with three new
chapters covering nanotechnology, engineering, and autopsy
labs

* Part III, Laboratory Support Services, addresses design issues
for imaging facilities, support shops, hazardous waste facilities,
and laboratory storerooms

* Part IV, HVAC Systems, explains how to heat, cool, and
ventilate labs with an eye towards energy conservation

* Part V, Administrative Procedures, deals with bidding
procedures, final acceptance inspections, and sustainability

The final part of the book features five appendices filled with
commonly needed data and reference materials.

This Fourth Edition is indispensable for all laboratory
design teams, whether constructing a new laboratory or renovating
an old facility to meet new objectives.

LOUIS J. DiBERARDINIS, BS, MS, CIH, CSP, is the Director
of Environment, Health, and Safety at MIT. He is a visiting
lecturer at Harvard University School of Public Health and Adjunct
Professor at the University of Massachusetts Lowell in the
Department of the Work Environment. He received his BS in chemical
engineering from Northeastern University and an MS in industrial
hygiene from Harvard University.

JANET S. BAUM, BS, MArch, AiA, currently teaches
part-time at Harvard University School of Public Health and at both
the Graduate School of Architecture and Urban Design and the
Institute of Public Health, Washington University in St. Louis. She
earned her BS in architectural sciences at Washington University in
St. Louis and her master of architecture at Harvard University
Graduate School of Design.

The late MELVIN W. FIRST, ScD, CIH, PE, was a researcher
and professor of environmental health Engineering at the Harvard
School of Public Health for almost sixty years and was actively
involved in research until a week before his death.

GARI T. GATWOOD, BSME, CSP (retired), is a consultant in
safety engineering. He has forty years of safety experience in
missile defense, commercial chemicals, laboratories, and university
programs. He holds a degree in mechanical engineering from the
Missouri School of Mines and Metallurgy in Rolla, Missouri.

Anand K. Seth, BS, MS, PE, CEM, CPE, is currently an
Engineering Principal in Cannon Design, an international
architectural/engineering firm. Seth worked at Massachusetts
General Hospital as director of engineering and at Harvard
University. He holds a master of science in mechanical engineering
from the University of Maine and has done postgraduate work at
other universities.

Proven and tested guidelines for designing ideal labs for scientific investigations

Now in its Fourth Edition, Guidelines for Laboratory Design continues to enable readers to design labs that make it possible to conduct scientific investigations in a safe and healthy environment. The book brings together all the professionals who are critical to a successful lab design, discussing the roles of architects, engineers, health and safety professionals, and laboratory researchers. It provides the design team with the information needed to ask the right questions and then determine the best design, while complying with current regulations and best practices.

Guidelines for Laboratory Design features concise, straightforward advice organized in an easy-to-use format that facilitates the design of safe, efficient laboratories. Divided into five sections, the book records some of the most important discoveries and achievements in:

• Part IA, Common Elements of Laboratory Design, sets forth technical specifications that apply to most laboratory buildings and modules
• Part IB, Common Elements of Renovations, offers general design principles for the renovation and modernization of existing labs
• Part II, Design Guidelines for a Number of Commonly Used Laboratories, explains specifications, best practices, and guidelines for nineteen types of laboratories, with three new chapters covering nanotechnology, engineering, and autopsy labs
• Part III, Laboratory Support Services, addresses design issues for imaging facilities, support shops, hazardous waste facilities, and laboratory storerooms
• Part IV, HVAC Systems, explains how to heat, cool, and ventilate labs with an eye towards energy conservation
• Part V, Administrative Procedures, deals with bidding procedures, final acceptance inspections, and sustainability

The final part of the book features five appendices filled with commonly needed data and reference materials.

This Fourth Edition is indispensable for all laboratory design teams, whether constructing a new laboratory or renovating an old facility to meet new objectives.

Foreword xv

Preface xvii

Acknowledgments xix

About the Authors xxi

Abbreviations xxiii

Units xxv

Organizations Referenced xxvii

Introduction xxix

How to Use This Book xxx

Book Organization xxxi

Computational Fluid Dynamics xxxiii

Part IA Common Elements of Laboratory Design 1

1 Building Considerations 3

1.1 Guiding Concepts 3

1.2 Building Layout 3

1.3 Guiding Principles for Building Heating Ventilating and Air-Conditioning Systems 44

1.4 Guiding Concepts for Laboratory Building Loss Prevention Industrial Hygiene and Personal Safety 51

1.5 Miscellaneous Services 56

2 Laboratory Considerations 65

Part IB Common Elements of Renovations 109

3 Renovations: Building Considerations 123

3.1 Guiding Concepts 123

3.2 Building Layout 125

3.3 Heating Ventilating and Air-Conditioning Systems 129

3.4 Loss Prevention Industrial Hygiene and Personal Safety 133

3.5 Miscellaneous Services 134

4 Renovations: Laboratory Considerations 136

4.1 Guiding Concepts 136

4.2 Laboratory Layout 137

4.3 Heating Ventilating and Air-Conditioning Systems 138

4.4 Loss Prevention Industrial Hygiene and Personal Safety 138

Part II Design Guidelines for a Number of Commonly Used Laboratories 141

5 General or Analytical Chemistry Laboratory 143

5.1 Description 143

5.2 Laboratory La…