This comprehensive book serves as a guide in the day-to-day management of patients with idiopathic inflammatory myopathies (IIM), with a particular emphasis on adult dermatomyositis (DM), polymyositis (PM), juvenile dermatomyositis, necrotizing myositis, and inclusion body myositis. Practical in nature, it presents IIM concepts in a straightforward fashion, with high-quality figures, algorithms, and flowcharts supplementing each of the expertly authored chapters. The book begins with an introduction to myositis, providing an overview of the myositis basics and what type of patient is affected. Subsequent chapters are organized by the sequence in which a physician often manages myositis, from initial presentation and workup, to diagnosis, treatment, and finally prognostic and long-term outcome factors. The key differentials in various diagnostic studies are thoroughly examined, including electromyography, muscle biopsy, and MRI. Managing Myositis: A Practical Guide is an easyto-read, indispensable resource for internists, rheumatologists, dermatologists, pulmonologists, and neurologists.
Autorentext
Rohit Aggarwal, MD, MS
Associate Professor of Medicine
University of Pittsburgh
School of Medicine
Medical Director, Arthritis and Autoimmunity Center
Co-Director of the UPMC Myositis Center
Pittsburgh, PA 15260
USA
Chester V. Oddis, MD
Professor of Medicine
University of Pittsburgh
School Of Medicine
Director of the Myositis Center
Pittsburgh, PA 15260
USA
Inhalt
Foreword1Introduction to Myositis
2Myositis Basics/Who Gets Myositis
3Evaluating the patient with suspected myositis
4Asymptomatic HyperCKemia
5Clinical Features of Myositis Patients: Muscular Manifestations
6Clinical Features of Myositis Patients: Skin Manifestations
7Clinical Features of Myositis Patients: Lung Manifestations
8Clinical Features of Myositis Patients: Cardiac Manifestations
9Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features
10Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional
11Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis
12Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing
13Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation
14Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation 15Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation
16Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI
17Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis
18Role of ANA and Myositis Autoantibodies in Diagnosis
19Role of Myositis Autoantibodies in Management and Prognosis
20Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP
21Dermatomyositis-associated Autoantibodies: TIF1-, NXP2, and MDA5
22Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60
23Myositis Mimics: The Differential Diagnosis of Myositis
24Immune Mediated Necrotizing Myopathy (IMNM)
25Cancer Associated Myositis
26Myositis Associated Interstitial Lung Disease
27Pregnancy in Myositis
28Pathogenesis of Myositis
29Management Considerations: Pharmacologic intervention
30Management Considerations:Special treatment considerations - JDM
31Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis
32Management Considerations: Special treatment considerations - ILD
33Role of Exercise in the Management of Myositis
34Dietary Considerations in Myositis
35Distinguishing Disease Activity and Damage in Myositis
