The first comprehensive overview of preprocessing, mining,
and postprocessing of biological data
Molecular biology is undergoing exponential growth in both the
volume and complexity of biological data--and knowledge
discovery offers the capacity to automate complex search and data
analysis tasks. This book presents a vast overview of the most
recent developments on techniques and approaches in the field of
biological knowledge discovery and data mining (KDD)--providing
in-depth fundamental and technical field information on the most
important topics encountered.
Written by top experts, Biological Knowledge Discovery
Handbook: Preprocessing, Mining, and Postprocessing of Biological
Data covers the three main phases of knowledge discovery (data
preprocessing, data processing--also known as data
mining--and data postprocessing) and analyzes both verification
systems and discovery systems.
BIOLOGICAL DATA PREPROCESSING
* Part A: Biological Data Management
* Part B: Biological Data Modeling
* Part C: Biological Feature Extraction
* Part D Biological Feature Selection
BIOLOGICAL DATA MINING
* Part E: Regression Analysis of Biological Data
* Part F Biological Data Clustering
* Part G: Biological Data Classification
* Part H: Association Rules Learning from Biological Data
* Part I: Text Mining and Application to Biological Data
* Part J: High-Performance Computing for Biological Data
Mining
Combining sound theory with practical applications in molecular
biology, Biological Knowledge Discovery Handbook is ideal
for courses in bioinformatics and biological KDD as well as for
practitioners and professional researchers in computer science,
life science, and mathematics.
Autorentext
MOURAD ELLOUMI is a Full Professor in Computer Science at the University of Tunis-El Manar, Tunisia. He is the author/coauthor of more than fifty publications in international journals and conference proceedings and the coeditor, along with Albert Zomaya, of Algorithms in Computational Molecular Biology: Techniques, Approaches and Applications (Wiley).
ALBERT Y. ZOMAYA is the Chair Professor of High Performance Computing & Networking at The University of Sydney's School of Information Technologies. He is the author/coauthor of seven books, more than 450 publications in technical journals and conference proceedings, and the editor of fourteen books and nineteen conference volumes. He is a Fellow of the IEEE, the American Association for the Advancement of Science, and IET (UK).
Klappentext
The first comprehensive overview of preprocessing, mining, and postprocessing of biological data
Molecular biology is undergoing exponential growth in both the volume and complexity of biological data—and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD)—providing in-depth fundamental and technical field information on the most important topics encountered.
Written by top experts, Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data covers the three main phases of knowledge discovery (data preprocessing, data processing—also known as data mining—and data postprocessing) and analyzes both verification systems and discovery systems.
BIOLOGICAL DATA PREPROCESSING
- Part A: Biological Data Management
- Part B: Biological Data Modeling
- Part C: Biological Feature Extraction
- Part D Biological Feature Selection
BIOLOGICAL DATA MINING
- Part E: Regression Analysis of Biological Data
- Part F Biological Data Clustering
- Part G: Biological Data Classification
- Part H: Association Rules Learning from Biological Data
- Part I: Text Mining and Application to Biological Data
- Part J: High-Performance Computing for Biological Data Mining
Combining sound theory with practical applications in molecular biology, Biological Knowledge Discovery Handbook is ideal for courses in bioinformatics and biological KDD as well as for practitioners and professional researchers in computer science, life science, and mathematics.
Inhalt
PREFACE xiii
CONTRIBUTORS xv
SECTION I BIOLOGICAL DATA PREPROCESSING
PART A: BIOLOGICAL DATA MANAGEMENT
1 GENOME AND TRANSCRIPTOME SEQUENCE DATABASES FOR DISCOVERY, STORAGE, AND REPRESENTATION OF ALTERNATIVE SPLICING EVENTS 5
Bahar Taneri and Terry Gaasterland
2 CLEANING, INTEGRATING, AND WAREHOUSING GENOMIC DATA FROM BIOMEDICAL RESOURCES 35
Fouzia Moussouni and Laure Berti-Equille
3 CLEANSING OF MASS SPECTROMETRY DATA FOR PROTEIN IDENTIFICATION AND QUANTIFICATION 59
Penghao Wang and Albert Y. Zomaya
4 FILTERING PROTEINPROTEIN INTERACTIONS BY INTEGRATION OF ONTOLOGY DATA 77
Young-Rae Cho
PART B: BIOLOGICAL DATA MODELING
5 COMPLEXITY AND SYMMETRIES IN DNA SEQUENCES 95
Carlo Cattani
6 ONTOLOGY-DRIVEN FORMAL CONCEPTUAL DATA MODELING FOR BIOLOGICAL DATA ANALYSIS 129
Catharina Maria Keet
7 BIOLOGICAL DATA INTEGRATION USING NETWORK MODELS 155
Gaurav Kumar and Shoba Ranganathan
8 NETWORK MODELING OF STATISTICAL EPISTASIS 175
Ting Hu and Jason H. Moore
9 GRAPHICAL MODELS FOR PROTEIN FUNCTION AND STRUCTURE PREDICTION 191
Mingjie Tang, Kean Ming Tan, Xin Lu Tan, Lee Sael, Meghana Chitale, Juan Esquivel-Rodrýguez, and Daisuke Kihara
PART C: BIOLOGICAL FEATURE EXTRACTION
10 ALGORITHMS AND DATA STRUCTURES FOR NEXT-GENERATION SEQUENCES 225
Francesco Vezzi, Giuseppe Lancia, and Alberto Policriti
11 ALGORITHMS FOR NEXT-GENERATION SEQUENCING DATA 251
Costas S. Iliopoulos and Solon P. Pissis
12 GENE REGULATORY NETWORK IDENTIFICATION WITH QUALITATIVE PROBABILISTIC NETWORKS 281
Zina M. Ibrahim, Alioune Ngom, and Ahmed Y. Tawfik
PART D: BIOLOGICAL FEATURE SELECTION
13 COMPARING, RANKING, AND FILTERING MOTIFS WITH
CHARACTER CLASSES: APPLICATION TO BIOLOGICAL SEQUENCES ANALYSIS 309
Matteo Comin and Davide Verzotto
14 STABILITY OF FEATURE SELECTION ALGORITHMS AND ENSEMBLE FEATURE SELECTION METHODS IN
BIOINFORMATICS 333
Pengyi Yang, Bing B. Zhou, Jean Yee-Hwa Yang, and Albert Y. Zomaya
15 STATISTICAL SIGNIFICANCE ASSESSMENT FOR BIOLOGICAL FEATURE SELECTION: METHODS AND ISSUES 353
Juntao Li, Kwok Pui Choi, Yudi Pawitan, and Radha Krishna Murthy Karuturi
16 SURVEY OF NOVEL FEATURE SELECTION METHODS FOR CANCER CLASSIFICATION 379
Oleg Okun
17 INFORMATION-THEORETIC GENE SELECTION IN EXPRESSION DATA 399
Patrick E. Meyer and Gianluca Bontempi
18 FEATURE SELECTION AND CLASSIFICATION FOR GENE EXPRESSION DATA USING EVOLUTIONARY COMPUTATION 421
Haider Banka, Suresh Dara, and Mourad Elloumi
SECTION II BIOLOGICAL DATA MINING
PART E: REGRESSION ANALYSIS OF BIOLOGICAL DATA
19 BUILDING VALID REGRESSION MODELS FOR BIOLOGICAL DATA USING STATA AND R 445
Charles Lindsey and Simon J. Sheather
20 LOGISTIC REGRESSION IN GENOMEWIDE ASSOCIATION ANALYSIS 477
Wentian Li and Yaning Yang
21 SEMIPARAMETRIC REGRESSION METHODS IN LONGITUDINAL DATA: APPLICATIONS TO AIDS CLINICAL TRIAL DATA 501
Yehua Li
PART F: BIOLOGICAL D…