Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment. - Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications - Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment - Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers



Autorentext

Muhammad Raza Shah is Full Professor at the International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry University of Karachi, Pakistan. He is also the Head of the Center for Bioequivalence Studies and Clinical Research (CBSCR) and the recipient of numerous awards, including the civil award Tamgha-i-Imtiaz from the President of Pakistan, Salam prize, Prof. Atta ur Rahman gold medal and the Dr. M. Raziuddin Siddiqi Prize (2015) for Scientists under 40 in the Field of Chemistry by the Pakistan Academy of Sciences. He was selected TWAS Young Affiliate in 2010 by Third World Academy of Sciences. He has authored three books (Elsevier) and also edited two books (Elsevier) in addition contributing over 350 peer-reviewed journal papers with impact factor more than 820. One of his authored books was declared best book of year 2017 by Government of Pakistan, Higher Education Commission. He is fellow International Union of Pure and Applied Chemistry and Fellow the Chemical Society of Pakistan. He is editor the Journal of the Chemical Society of Pakistan. He is mentor of Pakistani International Chemistry Olympiad team since 2009. He is also member of National Nanotechnology Foresight Committee constituted by PCST. He remained a member of COMSTECH consultative working group of scientists from OIC countries, to prepare agenda and action plan for the Ten-Year Plan of Action (TYPOA 2016-2025).



Klappentext

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites.

This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment.

  • Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications
  • Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment
  • Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers



Inhalt

1. Potential physical and biological barriers leading to failure of cancer chemotherapy
2. Nanotechnological strategies involved in the targeted delivery of anti-cancer drugs
3. Liposome based targeted delivery of anticancer drugs and effective therapy of tumors
4. Organic ligands as nanocarrier for targeted delivery of mediated active drug targeting for liver cancer
5. Surface functionalized magnetic nanoparticles in cancer drugs delivery and diagnosis
6. Nano-carriers based targeted pulmonary delivery: Novel approaches for effective lung cancer treatment
7. Enhancing therapeutic efficacy of anticancer drugs through functionalized niosomes targeting
8. Carbon nanotubes: Versatile nanocarriers for effective delivery of anti-cancer drugs
9. Construction of stimulus responsive micelles systems for efficient targeting of cancer drugs
10. Nano-targeted radiopharmaceuticals for cancer diagnosis and treatment
11. Potential role of gold nanoparticles in cancer diagnosis and targeted drug delivery

Titel
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy
EAN
9780128163115
Format
E-Book (epub)
Veröffentlichung
13.07.2019
Digitaler Kopierschutz
Wasserzeichen
Dateigrösse
4.28 MB
Anzahl Seiten
310