Adverse Reactions to Drugs, Second Edition focuses on the problems posed by the adverse responses to drugs, as well as drug interactions, dosage, and drug metabolism.
The publication first tackles adverse reactions and factors which predispose to adverse drug reactions. Topics include dose adjustment, overdose, renal failure, cumulation, side effects, drug allergy, cumulative overdose, and delayed effects. The text then ponders on drug interactions, including renal excretion, drug metabolism, mutual toxicity, and interactions affecting transport to site of action.
The manuscript examines adverse reactions in dental practice, drugs used in pregnancy, the neonate, and lactation, and problems for the pharmaceutical industry before marketing a new drug. Discussions focus on ethical problems of drug studies in man, pregnancy, hemorrhage, oxygen toxicity, chloramphenicol, drugs and lactation, drugs used in dental practice, and local anesthetics. The book then elaborates on monitoring adverse reactions to drugs and the therapeutic audit and drug regulatory bodies and their problems.
The publication is a valuable source of data for doctors and dentists wanting to focus on research on the adverse reaction to drugs.
Inhalt
Preface to Second Edition
Acknowledgments
Chapter I The Dawn of Concern
Chapter I1 Adverse Reactions
Chapter I11 Factors which Predispose to Adverse Reactions
Chapter IV Drug Interactions
Chapter V Adverse Reactions in Dental Practice
Chapter VI Drugs used in Pregnancy the Neonate and Lactation
Chapter VII Problems for the Pharmaceutical Industry Before Marketing a New Drug
Chapter VIII Monitoring Adverse Reactions to Drugs and the Therapeutic Audit
Chapter IX Drug Regulatory Bodies and their Problems
Chapter X The Future
Appendix I Adverse Reactions to Drugs
Appendix I1 Drug Induced Disease
Appendix I11 Drugs Interaction Tables
Appendix IV Drugs in Pregnancy
References
Index
Drug Index