Herbal complexing agents, which encompass both active phytoconstituents and pharmaceutical excipients, provide novel approaches to addressing these issues by employing various molecular complexation mechanisms. This book goes into detail about the basic ways that complexation works, such as supramolecular interactions, inclusion complexation (like cyclodextrins), phyto-phospholipid complexation (like phytosomes/herbosomes), and metal chelation. It goes into more detail about their important uses in the pharmaceutical industry, such as improving drug formulation and delivery, which makes drugs more soluble, stable, and available to the body, and allowing for more advanced drug delivery systems.
Autorentext
Raj Keshwar Prasad is an Associate Professor at Shambhunath Institute of Pharmacy, Jhalwa, Prayagraj, AKTU Lucknow, with seventeen years of teaching experience dating back to August 16, 2008. He holds an M. Pharm. in Pharmaceutical Chemistry with 74.5% from the Department of School of Pharmacy, Devi Ahilya Vishwavidyalaya (DAVV), Indore, in 2008.Prasad is a Ranbaxy Gold Medalist for academic excellence in M. Pharm (Pharmaceutical Chemistry) at DAVV, Indore. He qualified for the national-level GATE exam in 2005 (95.45 percentile, AIR-520) and 2006 (92 percentile), conducted by the Ministry of Human Resource and Development, Govt. of India, for higher studies. He was also awarded fellowships by AICTE, Govt. of India, during his M. Pharm program. In 2022, he successfully completed a 12-week NPTEL online certification course in medicinal chemistry with 72% (Elite) from the Indian Institute of Science Education and Research (IISER), Pune, funded by the MoE, Government of India.His expertise includes handling analytical instruments like HPLC, UV Spectrophotometer, and FT-IR , and using software for Molecular Modeling, Homology Modeling, and Drug Designing such as Schrodinger, Chem-Office, V Life, SPD viewers, MOE, and AutoDOCK. He is proficient in QSAR studies (2D QSAR, 3D QSAR, and Hansch QSAR), Pharmacophore, molecular descriptors, Molecular Docking, and Correlation analysis (MLR, PCA, and PLS). His skills also extend to Chemoinformatics and computational chemistry, including Pharmacophore modeling, computational Drug designing, Analog Structure-based drug design, and discovery. He is experienced in the synthesis of various Heterocyclic and medicinal compounds and Microwave-assisted Synthesis.