From a biomedical engineering perspective, this book takes an analytic, quantitative approach to describing the basic components of physiological regulators and control systems (PRCs). In Endogenous and Exogenous Regulation and Control of Physiological Systems, the author provides grounding in the classical methods of designing linear and nonlinear systems. He also offers state-of-the-art material on the potential of PRCs to treat immune system ailments, most notably AIDS and cancer. The book focuses on certain "wet" physiological regulators, such as those using endocrine hormones as parametric control substances. Endogenous and Exogenous Regulation and Control of Physiological Systems includes simulations that illustrate model validations and the putative control of cancer and HIV proliferation. It explores novel, untried immunotherapies on the cutting-edge of PRC treatment and explores the latest technologies.

Robert B. Northrop (University of Connecticut, Storrs, USA) (Author)

Introduction to Physiological Regulators and Control Systems. Physical and Chemical Factors Governing the Behavior of PRCs. Introduction to Compartmental Modeling and Pharmacokinetic Systems. Special Types of Closed-Loop Drug Input Controllers. Regulation of Blood Glucose. Control of Mean Arterial Pressure by Sodium Nitroprusside Injection. Control of Post-Operative Pain by Self-Administered Opioids. The Human Immune System Seen from a Biomedical Engineering Viewpoint. Some Simulation Packages Suitable for Modeling Nonlinear Systems.


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