Curriculum Integration outlines and presents a curriculum integration matrix for 21st century learning in complex and diverse information environments. The curriculum integration matrix is based on the constructivist instructional framework of Guided Inquiry and underpinned by the Information Search Process, both developed by Carol Kuhlthau, Professor Emerita, Rutgers University. It outlines how Guided Inquiry as an instructional framework in 21st century schools can be developed and implemented to enable students to learn meaningfully from diverse and complex information sources.