This is the second edition of a very successful title from an international team of highly respected opinion leaders. Its emphasis remains on how the clinical guidelines are to be interpreted effectively in everyday practice, and as such it has immense practical importance for clinical psychiatrists as an immediate source of reference. New to this

Sidney H. Kennedy, Raymond W. Lam, David J. Nutt, Micael E. Thase

Prevalence, burden and diagnosis. Principles of management. Psychotherapies, alone and in combination with pharmacotherapy. Evolution of antidepressant agents. Evidence based antidepressant selection across depressive disorders. Practical issues in using antidepressants. Sequential pharmacotherapies and treatment-resistant depression. Neuromlodulation and other physical treatments. Complementary, light, sleep deprivation and exercise therapies. Depression in women. Depression in children and adolescents. Depression in late life. Psychiatric and physical comorbidities in depression.