This introductory reference provides a practical, concise summary of everything a physician needs to know about genomics and emerging technologies. Through extensive illustrative examples, this book offers a clear and concise starting point to understanding how medicine has been, and will be, transformed by genomics and bioinformatics. Beginning with a clear overview on the Human Genome Project and its revolutionary impact, the book further investigates new technologies in detail, including: high-throughput DNA sequencing, genome sequence databases, microarrays, proteomics, pharmacogenomics, genetic testing, and gene therapy.
Autorentext
Dr. Stuart M. Brown is in the faculty of New York University School of Medicine, where he is Associate Professor and Director of the Bioinformatics Core Facility and director for the graduate course "Using Computers in Molecular Biology."
Klappentext
New and emerging technologies, particularly in the areas of molecular genetic diagnostics and gene therapy, are having an unprecedented impact on medicine. Physicians and medical students need to understand these revolutionary developments and their role in clinical practice. Stuart Brown’s Essentials of Medical Genomics fills this need, providing a concise, clearly written guide to the state of the art in genomic research, and explaining in easy-to-follow terms how it is changing the way patients are diagnosed and treated.
Richly illustrated throughout, each chapter in Essentials of Medical Genomics focuses on the informational needs of practitioners. Beginning with a clear overview on the Human Genome Project and its revolutionary impact, this "essentials only" guide then covers such key topics as bioinformatics and online resources for practitioners. Other chapter topics include:
- Genetic testing
- Microarray analysis
- Proteomics
- Genome databases
- Pharmacogenomics and toxicogenomics
- Gene therapy
- Ethical considerations
Essentials of Medical Genomics is the first of its kind to provide a practical introduction to genomics as it impinges upon clinical practice. Medical students and physicians will benefit handsomely from this pioneer text.
Inhalt
Preface.
Acknowledgments.
Deciphering the Human Genome Project.
Genomic Technology.
Bioinformatics Tools.
Genome Databases.
Human Genetic Variation.
Genetic Testing for the Practitioner (H. Ostrer).
Gene Therapy (J. Hay).
Microarrays.
Pharmacogenomics and Toxicogenomics.
Proteomics.
The Ethics of Medical Genomics.
Glossary.
Index.