Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment. - Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments - Discusses new applications of camptothecin based on recent biotechnology advancements - Presents comprehensive information on the pharmacology of camptothecin for leveraging new anticancer drugs developments
Autorentext
Prof. T.Pullaiah has retired from active service in 2011 and then was UGC-BSR Faculty Fellow in the Department of Botany, Sri Krishnadevaraya University, Anantapur, India. He has published 75 books, 330 research papers, and 35 popular articles. He was the President of Indian Association for Angiosperm Taxonomy (2013) and the President of the Indian Botanical Society (2014). He has been a member of Species Survival Commission of International Union for Conservation of Nature and Natural Resources (IUCN).
Inhalt
1. Cancer biology and other disorders: beneficial role of camptothecin and novel derivatives
2. Camptothecin: chemistry, biosynthesis, analogs, and chemical synthesis
3. Camptothecin and analogs: role in anticancer activities
4. Botany of camptothecin-yielding plants
5. Propagation of camptothecin biosynthesizing plants
6. In vitro camptothecin production from plants: prospects and challenges
7. Biomining of camptothecin producing plants through molecular techniques
8. Endophytes and camptothecin production