Alpha-1 antitrypsin deficiency, one of the most common genetic disorders among Caucasians, is still an under-recognized disease. Identification of patients and establishing sufficient preventive and therapeutic measures necessitates at least a basic level of knowledge about alpha-1 antitrypsin deficiency among medical professionals. The authors intend to provide basic information about the most important aspects of alpha-1 antitrypsin deficiency in a short and comprehensive style. This book may serve as a valuable source of information for clinical aspects and management of patients.