The guide to effective practice management of precancerous
lesions in cervix and lower genital tract.

This third edition contains in-depth examination of the
different modalities that contribute to the safe and scientific
management of precancerous lesions in the female genital tract. One
of the most important is colposcopy which provides an accurate and
effective route to their identification.

Professor Albert Singer is internationally recognized as a
master of colposcopy. His training courses throughout the world are
in high demand. In this edition, he has teamed with fellow expert
Ashfaq Khan to present a very accessible, authoritative and highly
illustrated guide to the power of colposcopy.

Practical pictorial guidance to recognizing potentially
cancerous abnormalities in the cervix, vagina, and vulva is framed
by internationally agreed disease classifications. Consensus
guidelines from the US and Europe provide a rigorous platform for
management advice. The latest information on HPV, the role of
biomarkers, and new methods in diagnosis and treatment are all
featured.

Cervical and Lower Genital Tract Precancer is the ideal
companion for anyone wishing to incorporate safe and scientific
methods of diagnosis and treatment into their clinical
practice.

ALBERT SINGER, MB BS, PhD DPhil, FRCOG, Emeritus Professor of Gynecology and Consultant in Obstetrics and Gynecology, Whittington Hospital, London, UK; and Quality Assurance lead for colposcopy in London.

ASHFAQ KHAN, MB BS, FRCOG, Consultant Gynecologist at the Whittington Hospital, London, UK.

Klappentext

Singer & Monaghan's Cervical and Lower Genital Tract Precancer: Diagnosis and Treatment, Third Edition

Albert Singer,PhD (Sydney), DPhil (Oxon), FRCOG

Professor (Emeritus) of Gynecological Research, University of London, UK

Consultant Gynecologist (Hon), Whittington Health NHS Trust, London

Ashfaq M. Khan, MBBS, FRCOG

Consultant Gynecologist

Lead Colposcopist

Whittington Health NHS Trust, London, UK

The guide to effective practice management of precancerous lesions in cervix and lower genital tract.This third edition contains in-depth examination of the different modalities that contribute to the safe and scientific management of precancerous lesions in the female genital tract. One of the most important is colposcopy which provides an accurate and effective route to their identification.

Professor Albert Singer is internationally recognized as a master of colposcopy. His training courses throughout the world are in high demand. In this edition, he has teamed with fellow expert Ashfaq Khan to present a very accessible, authoritative and highly illustrated guide to the power of colposcopy.

Practical pictorial guidance to recognizing potentially cancerous abnormalities in the cervix, vagina, and vulva is framed by internationally agreed disease classifications. Consensus guidelines from the US and Europe provide a rigorous platform for management advice. The latest information on HPV, the role of biomarkers, and new methods in diagnosis and treatment are all featured.

Cervical and Lower Genital Tract Precancer is the ideal companion for anyone wishing to incorporate safe and scientific methods of diagnosis and treatment into their clinical practice.

www.colposcopycourses.com

Titles of related interest

Bonney's Gynaecological Surgery, 11th Edition

Tito Lopes, Nick Spirtos, Raj Naik, John M. Monaghan

ISBN: 978-1-4051-9565-2

The Cervix 2e

Edited by Joseph Jordan Albert Singer, Howard Jones and Mahmood Shafi

ISBN: 978-1-4051-3137-7

www.wiley.com/go/obgyn

The guide to effective practice management of precancerous lesions in cervix and lower genital tract.

This third edition contains in-depth examination of the different modalities that contribute to the safe and scientific management of precancerous lesions in the female genital tract. One of the most important is colposcopy which provides an accurate and effective route to their identification.

Professor Albert Singer is internationally recognized as a master of colposcopy. His training courses throughout the world are in high demand. In this edition, he has teamed with fellow expert Ashfaq Khan to present a very accessible, authoritative and highly illustrated guide to the power of colposcopy.

Practical pictorial guidance to recognizing potentially cancerous abnormalities in the cervix, vagina, and vulva is framed by internationally agreed disease classifications. Consensus guidelines from the US and Europe provide a rigorous platform for management advice. The latest information on HPV, the role of biomarkers, and new methods in diagnosis and treatment are all featured.

Cervical and Lower Genital Tract Precancer is the ideal companion for anyone wishing to incorporate safe and scientific methods of diagnosis and treatment into their clinical practice.

Preface to the Third Edition ix

Preface to the First Edition x

Acknowledgements xi

1 The Histopathology of Lower Genital Tract Neoplasia 1

1.1 Introduction 1

1.2 Terminology 1

1.3 Histopathologic features of cervical intraepithelial neoplasia or squamous intraepithelial lesion 3

1.4 Cervical glandular intraepithelial neoplasia and adenocarcinoma in situ 6

1.5 Early invasive carcinoma 7

1.6 Vaginal intraepithelial neoplasia 11

1.7 Vulval precancer 11

1.8 Related topics 12

1.9 Further reading 13

2 Human Papillomaviruses in the Pathogenesis of Lower Genital Tract Neoplasia 14

2.1 Introduction 14

2.2 Characteristics of human papillomaviruses 14

2.3 Manifestations of genital human papillomavirus infections 15

2.4 Prevalence of genital human papillomavirus infections 18

2.5 Transmission of genital human papillomavirus infections 19

2.6 Risk factors for genital human papillomavirus infections 19

2.7 Natural history of cervical human papillomavirus infections 19

2.8 Molecular pathways of human papillomavirus oncogenesis 19

2.9 The effect of human papillomavirus/host cell interaction: a prerequisite for neoplasia 21

2.10 The role of oncogenic human papillomavirus detection in the prevention of lower genital tract precancer 22

2.11 Further reading 23

3 Examination for Cervical Precancer: Use of colposcopy 24

3.1 Introduction 24

3.2 Tissue basis for colposcopy 24

3.3 The colposcopic examination 25

3.4 Video colposcopy 31

3.5 Image and electronic data management 31

3.6 Further reading 32

4 Colposcopy of the Normal Cervix: A prerequisite to establishing the diagnosis of cervical precancer 33

4.1 Introduction 33

4.2 Cervical epithelium: natural histor…