Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. - BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association - Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology - Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins - Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging - Offers readers clear, visual representation of structural concepts through full colour figures throughout the book
Inhalt
PREFACE
GLOSSARY
CHAPTER 1: CHEMIOSMOTIC ENERGY TRANSDUCTION
CHAPTER 2: ION TRANSPORT ACROSS ENERGY-CONSERVING MEMBRANES
CHAPTER 3: QUANTITATIVE BIOENERGETICS: THE MEASUREMENT OF DRIVING FORCES
CHAPTER 4: THE CHEMIOSMOTIC PROTON CIRCUIT IN ISOLATED ORGANELLES: THEORY AND PRACTICE
CHAPTER 5: RESPIRATORY CHAINS
CHAPTER 6: PHOTOSYNTHETIC GENERATORS OF PROTONMOTIVE FORCE
CHAPTER 7: THE ATP SYNTHASE
CHAPTER 8: METABOLITE AND ION TRANSPORT
CHAPTER 9: MITOCHONDRIAL BIOENERGETICS IN THE CELL
CHAPTER 10 MITOCHONDRIAL CELL BIOLOGY
CHAPTER 11: SIGNALS BETWEEN THE MITOCHONDRION AND THE CELL
CHAPTER 12: MITOCHONDRIA IN PHYSIOLOGY AND PATHOLOGY
REFERENCES
INDEX