Illustrating the differences between urgent interventions and interventions performed to manage chronic conditions the authors present the chapters in a consistent template for ease of use covering; background, indications, evidence review, device description, procedural techniques, follow-up care, and complications. * Shows the differences between interventions performed to manage chronic conditions and interventions that are truly urgent * Chapters follow a consistent structure from background through indications, evidence review, device description, procedural techniques to follow-up care and complications * More than 40 high definition videos, hosted on companion website href="http://www.wiley.com/go/kipshidze/interventionaltherapies">www.wiley.com/go/kipshidze/interventionaltherapies, complete with tips and tricks, provide a visual learning tool

Nicholas Kipshidze, MD, PhD, DSc, FACC, FESC, FSCAI, Professor of Medicine and Surgery, Director of Endovascular Therapies, New York Cardiovascular Research, New York, NY, USA; Consultant Cardiologist, N. Kipshidze Central University Hospital, Tbilisi, Georgia.

Jawed Fareed, PhD, FACB, Professor of Pathology and Pharmacology, Director of Hemostasis and Thrombosis Research Laboratories and Department of Pathology, Loyola University, Stritch School of Medicine, Maywood, IL, USA

Robert J. Rosen, MD, Director, Interventional Radiology and Endovascular Surgery, Lenox Hill Heart and Vascular Institute, New York, NY, USA

George Dangas, MD, PhD, FACC, FAHA, FESC, FSCAI, Professor of Cardiology and Vascular Surgery, Director, Cardiovascular Innovation, Mount Sinai Medical Center, New York, NY, USA

Patrick W. Serruys, MD, PhD, FESC, FACC, Emeritus Professor of Medicine, Chair in Interventional Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands; Professor of Cardiology, Imperial College, London, UK

Urgent Interventional Therapies focuses on the urgent interventional procedures performed in the most serious and critical cases of cardiovascular and peripheral artery diseases, where immediate specialist care is required, such as cardiac arrest, acute myocardial infarction, stroke, critical leg ischemia, aneurysm, and pulmonary embolism.

Illustrating the differences between urgent interventions and interventions performed to manage chronic conditions, the authors use a consistent structure for ease of use beginning with background, indications, evidence review, and device description, then moving to procedural techniques, follow-up care, and complications. Accompanying high-definition surgical videos, complete with tips and tricks, provide an additional visual learning tool.

The editors represent some of the world's leading experts in interventional cardiology and are supported by a stellar team of international authors who provide their expert knowledge and experience for each topic. A section on radiologic and experimental therapies covers potential treatments of the future, including cell therapy, aqueous oxygen therapy, cryotherapy, and therapeutic hypothermia.

Urgent Interventional Therapies will be invaluable to all interventionalists, specifically interventional cardiologists and radiologists who, as a result of an increasing call for urgent interventions, wish to expand their armamentarium of surgical and clinical skills.

List of Contributors, viii

Foreword, xv

Preface, xvii

Abbreviations, xviii

About the Companion Website, xxii

Part 1 Cardiac Interventions

Section I Acute Coronary Syndrome

1 Acute Coronary Syndrome: Guidelines and Definitions, 3
Elias A. Sanidas, Roxana Mehran & George Dangas

2 Cardiac Biomarkers in Acute Cardiac Care, 9
Jonathan D. Marmur, Sanjay Kumar & Antony L. Innasimuthu

3 Diagnosis of Vulnerable Plaque, 19
Konstantinos Toutouzas, Antonios Karanasos & Christodoulos Stefanadis

4 Management of Thrombotic Disorders: Heparin to Newer Anticoagulants, 27
Jawed Fareed, Evi Kalodiki & Debra Hoppensteadt

5 Newer Antiplatelet Agents for Interventional Indications, 41
Wiktor Kuliczkowski & Victor Serebruany

6 Genetic Considerations of Antiplatelet Therapy, 49
Fabiana Rollini, Antonio Tello-Montoliu & Dominick J. Angiolillo

7 Anticoagulant Management of Heparin-Compromised Patients, 60
Jeanine M. Walenga & Mamdouh Bakhos

8 Management of Bleeding in Urgent Interventions, 66
Rakesh Wahi & Debra Hoppensteadt

9 Role of Newer Anti-Xa and Anti-IIa Agents for Interventions, 77
Brigitte Kaiser

10 Treatment of NSTEMI Patients, 86
Kirk N. Garratt & Jonathon Habersberger

11 Treatment of Patients with STEMI, 91
Carsten Stengaard, Jacob Thorsted Sørensen, Christian Juhl Terkelsen & Michael Maeng

12 Mechanical Removal of Thrombus from Culprit Lesions: Current Devices and Future Developments, 99
Zoran Lasic

13 Role of Intravenous Fibrinolytic Therapy, 105
Freek W.A. Verheugt

14 The Transradial Approach in Patients with Acute Coronary Syndromes, 110
Jeffrey M. Schussler

15 Intervention for Failed Grafts, 117
Michael S. Lee & Gopi Manthripragada

16 Excimer Laser for Revascularization in AMI, 126
On Topaz, Allyne Topaz & Kristine Owen

17 Management of Patients Presenting too Late for PTCA, 137
Giampaolo Niccoli, Cristina Aurigemma & Filippo Crea

18 Is There a Role for Drug-Eluting Balloons in Treatment of Acute Coronary Syndromes?, 146
Anouar Belkacemi, Pierfrancesco Agostoni, Michiel Voskuil, Kevin Onsea, Pieter Doevendans & Pieter Stella

19 Cardiogenic Shock: Outcomes, Treatment, and Role of Hemodynamic Support, 152
Eugenia Nikolsky, Amit Soni & Rafael Beyar

20 Management of Patients after Acute Coronary Syndrome, 171
Davide Capodanno & George Dangas

21 Emergency PTCA or CABG for Left Main Disease?, 179
Gill Louise Buchanan, Alaide Chieffo & Antonio Colombo

Section II Urgent Electrophysiology

22 Management of Reperfusion Arrhythmias, 187
Zviad Matoshvili & Nicholas Kipshidze

23 Ablative Therapies in Arrhythmia Emergencies, 192
Francesco Santoni-Rugiu

Section III Other Acute Cardiac Conditions

24 Principles of Interventions in Acute Structural Heart Disease, 198
Jennifer Franke, Stefan C. Bertog, Ilona Hofmann & Horst Sievert

25 Acute Interventional Therapies for Pulmonary Embolism, 201
Ian del Conde & Barry T. Katzen

26 Transcatheter Aortic Valve Implantation, 209
Thomas M. Snow, Neil Moat, Simon Davies, Sarah Barker, Alison Duncan & Carlo di Mario

27 Acute Mitral Interventions, 221
José A. Condado, Carlos Calderas & José F. Condado

28 Mitral and Aortic Valve Balloon Valvotomy, 231
Sumith Aleti, Jawahar L. Mehta & Rajesh Sachdeva

29 Postinfarction Ventricular Septal Defect, 238
Holger Thiele, Steffen Desch, Gerhard Schu...