This issue of Hospital Medicine Clinics, edited by Dr. Rachel Thompson, covers a broad spectrum of topics including: Cardiovascular Risk Assessment and Modification; Pulmonary Risk Assessment and Optimization, Diabetes and Hyperglycemia in the Surgical Setting; Management of Anticoagulants and VTE Prevention; Planning for Perioperative Pain Management; Medication Management for Patients on Chronic Steroids or Rheumatalogics; Anesthesia Considerations for the Hospitalist; Perioperative Assessment Of and Care for the Elderly and Frail; Quality and Value in Perioperative Medicine; Risk Assessment and Perioperative Care for Patients with Renal or Liver Disease; and Surgical Site Infections!