Highly Commended at the BMA Book Awards 2013
Extreme Tissue Engineering is an engaging introduction to
Tissue Engineering and Regenerative Medicine (TERM), allowing the
reader to understand, discern and place into context the mass of
scientific, multi-disciplinary data currently flooding the
field. It is designed to provide interdisciplinary, ground-up
explanations in a digestible, entertaining way, creating a text
which is relevant to all students of TERM regardless of their route
into the field.
Organised into three main sections: chapters 1 to 3 introduce
and explain the general problems; chapters 4 to 6 identify
and refine how the main factors interact to create the problems and
opportunities we know all too well; chapters 7 to 9 argue us
through the ways we can use leading-edge (extreme) concepts to
build our advanced solutions.
Students and researchers in areas such as stem cell and
developmental biology, tissue repair, implantology and surgical
sciences, biomaterials sciences and nanobiomedicine,
bioengineering, bio-processing and monitoring technologies - from
undergraduate and masters to doctoral and post-doctoral research
levels - will find Extreme Tissue Engineering a stimulating
and inspiring text.
Written in a fluid, entertaining style, Extreme Tissue
Engineering is introductory yet challenging, richly illustrated
and truly interdisciplinary.
Autorentext
Robert A. Brown is Professor of Tissue Engineering and Director of the Centre for Tissue Regeneration Science at University College London, UK. He is also co-ordinator of the London Tissue Engineering Consortium (Tissue Bioreactor Science) and the British Tissue Engineering Network (BRITE Net), as well as current President of the Tissue and Cell Engineering Society (TCES). Professor Brown has published over 180 peer-reviewed publications and 18 patents/applications, collaborating across industry and academia to promote interdisciplinary research in Tissue Engineering and Regenerative Medicine
Klappentext
Extreme Tissue Engineeringis an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field.
Organised into three main sections: chapters 1 to 3 introduce and explain the general problems; chapters 4 to 6 identify and refine how the main factors interact to create the problems and opportunities we know all too well; chapters 7 to 9 argue us through the ways we can use leading-edge (extreme) concepts to build our advanced solutions.
Students and researchers in areas such as stem cell and developmental biology, tissue repair, implantology and surgical sciences, biomaterials sciences and nanobiomedicine, bioengineering, bio-processing and monitoring technologies - from undergraduate and masters to doctoral and post-doctoral research levels - will find Extreme Tissue Engineering a stimulating and inspiring text.
Written in a fluid, entertaining style, Extreme Tissue Engineeringis introductory yet challenging, richly illustrated and truly interdisciplinary.
- First introductory text in the field of tissue engineering and regenerative medicine
- Truly interdisciplinary, serving students and researchers in the basic science, clinical aspects and regulatory aspects of the field
- Uses real life examples to illustrate and educate
- Written in an original and entertaining style by one of the top experts in the field
- Published in full colour with clear, student-friendly illustrations
Zusammenfassung
Highly Commended at the BMA Book Awards 2013
Extreme Tissue Engineering is an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field.
Organised into three main sections: chapters 1 to 3 introduce and explain the general problems; chapters 4 to 6 identify and refine how the main factors interact to create the problems and opportunities we know all too well; chapters 7 to 9 argue us through the ways we can use leading-edge (extreme) concepts to build our advanced solutions.
Students and researchers in areas such as stem cell and developmental biology, tissue repair, implantology and surgical sciences, biomaterials sciences and nanobiomedicine, bioengineering, bio-processing and monitoring technologies - from undergraduate and masters to doctoral and post-doctoral research levels - will find Extreme Tissue Engineering a stimulating and inspiring text.
Written in a fluid, entertaining style, Extreme Tissue Engineering is introductory yet challenging, richly illustrated and truly interdisciplinary.
Inhalt
Preface: Extreme Tissue Engineering a User's Guide xi
1 Which Tissue Engineering Tribe Are You From? 1
1.1 Why do we need to engineer tissues at all? 1
1.1.1 Will the real tissue engineering and regenerative medicine please stand up? 2
1.1.2 Other people's definitions 3
1.1.3 Defining our tissue engineering: fixing where we are on the scale-hierarchy 4
1.2 Bio-integration as a fundamental component of engineering tissues 7
1.2.1 Bio-scientists and physical scientists/engineers: understanding diversity in TERM 8
1.3 What are the 'tribes' of tissue engineering? 10
1.3.1 Special needs for special characteristics: why is networking essential for TERM? 13
1.4 Surprises from tissue engineering (Veselius to Vacanti) 16
1.5 So really is there any difference between tissue engineering and regenerative medicine? 20
1.5.1 Questions never really asked: repair versus regeneration? 20
1.5.2 Understanding the full spectrum: tissue replacement repair and regeneration 23
1.6 Conclusions 27
1.7 Summarizing definitions 28
Annex 1 Other people's definitions of tissue engineering 29
Annex 2 Other people's definitions of regenerative medicine 30
Further reading 30
2 Checking Out the Tissue Groupings and the Small Print 33
2.1 Checking the small print: what did we agree to engineer? 33
2.2 Identifying special tissue needs problems and opportunities 37
2.3 When is 'aiming high' just 'over the top'? 39
2.4 Opportunities risks and problems 41
2.4.1 Experimental model tissues (as distinct from spare-parts and fully regenerated tissues) 41
2.4.2 The pressing need for 3D model tissues 42
2.4.3 Tissue models can be useful spin-offs on the way to implants 42
2.5 Special needs for model tissues 44
2.5.1 Cell selection: constancy versus correctness 44
2.5.2 Support matrices can synthetics fake it? 45
2.5.3 Tissue dimensions: when size does matter! 46
2.6 Opportunities and sub-divisions for engineering clinical implant tissues 46
2.6.1 Making physiological implants: spare parts or complete replacement? 47
2.6.2 Making pathological and aphysiological constructs: inventing new parts and new uses 47
2.6.3 Learning to use the plethora of tissue requirements as an opportunity 48
2.7 Overall summary 49
Further reading 49
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