The critical care management of patients with life-threatening neurological conditions requires the ability to treat neurological injuries, manage medical complications and perform invasive procedures whilst balancing the management of the brain and the body. The Oxford Textbook of Neurocritical Care provides an authoritative and up-to-date summary of the scientific basis, clinical techniques and management guidelines in this exciting clinical discipline. This highly authoritative textbook is conceptually divided into three sections. Section 1 provides an accessible guide to the general principles of neurophysiology and neuropharmacology, cardiorespiratory support, management of fluids and intracranial hypertension. Section 2 outlines the use of multiple monitoring modes which are crucial to diagnosis and management. Section 3 covers the management of the major pathologies encountered during neurointensive care with an emphasis on evidence-based practice or consensus guidelines to provide a cohesive and definitive clinical resource. Authored by an international team of expert practitioners this textbook reflects world-wide practice and guidelines. This volume is published with a concurrent online version, which features access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint ®. Designed for consultants and trainees in neurocritical care, The Oxford Textbook of Neurocritical Care is also accessible to the general critical care physician and trainees who need a definite and authoritative resource to meet the unique needs of neurocritically ill patients.

Part 1 General Principles; 1 Martin Smith: Introduction to neurocritical care; 2 RajaNandini Muralidharan and W Andrew Kofke: Applied neuropathophysiology and neuropharmacology; 3 Chandril Chugh and W Andrew Kofke: Cerebral blood flow physiology, pharmacology and pathophysiology; 4 Paolo Pelosi, Maria Vargas, and Iole Brunetti: Cardiorespiratory support in neurologic critically ill patients; 5 Jonathan Ball: Fluid management; 6 Mauro Oddo and Luzius A Steiner: Sedation and analgesia in the neurocritical care unit; 7 Andrea Lavinio: Intracranial hypertension; 8 Leslie M Whetstine, David W Crippen, and W Andrew Kofke: Ethical and legal issues in neurocritical care; Part 2 Monitoring; 9 Federico Villa and Giuseppe Citerio: Intracranial pressure monitoring; 10 Chandril Chugh and W Andrew Kofke: Monitoring cerebral blood flow; 11 Matthew A Kirkman and Martin Smith: Cerebral oxygenation monitoring; 12 Imoigele Aisiku and Claudia Robertson: Brain tissue biochemistry; 13 Hooman Kamel and Claude Hemphill III: Multimodal brain monitoring and neuroinformatics; 14 Neha S Dangayach and Jan Claassen: Electrophysiology in the intensive care unit; 15 Yanrong Zhang, Peter Komlosi, Mingxing Xie, and Max Wintermark: Neuroimaging; Part 3 Specific Conditions; 16 Nicolas Bruder and Lionel Velly: Postoperative care; 17 Hayden White and Bala Venkatesh: Traumatic brain injury; 18 Pouya Tahsili-Fahadan and Michael N Diringer: Subarachnoid haemorrhage; 19 Candice Delcourt and Craig Anderson: Intracerebral haemorrhage; 20 Barry M Czeisler, Daniel Sahlein, and Stephan A Mayer: Acute ischaemic stroke; 21 Jefferson R Wilson, Newton Cho, and Michael G Fehlings: Traumatic spinal cord injury; 22 Nicola Latronico and Nazzareno Fagoni: Neuromuscular disorders & acquired neuromuscular weakness; 23 Jan Novy and Andrea O Rossetti: Status epilepticus in adults; 24 Erich Schmutzhard, Ronny Beer, Raimund Helbok, and Bettina Pfausler: Central nervous system infection and inflammation; 25 Jerry P Nolan: Post cardiac arrest sydnrome; 26 Olivier Bodart, Aurore Thibaut, Steven Laureys, and Olivia Gosseries: Disorders of consciousness; 27 Derek J Roberts and David A Zygun: Non-neurological complications of acquired brain injury; 28 Adikarige Haritha Dulanka Silva, Antonio Belli, and Martin Smith: Electrolyte and endocrine disturbances; 29 Jeanne Teitelbaum and Sam Shemie: Brain death; 30 Ivan Rocha Ferreira da Silva and Jennifer A Frontera: Principles of organ donation; 31 Lakshmi P Chelluri and Jayaram Chelluri: Outcome after neurointensive care